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Drug interactions > Miscellaneous > Flashcards

Miscellaneous Flashcards

1
Q

Drugs causing ⬇️Na+

A

Loop diuretics e.g. indapamide
SSRIs esp. citalopram
Carbemazepine
Haloperidol

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2
Q

PPIs SE

A

⬇️Mg2+

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3
Q

Lidocaine max dose

A

3mg/kg plain
7mg/kg with adrenaline

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4
Q

Lidocaine max dose

A

3mg/kg plain
7mg/kg with adrenaline

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5
Q

Tacrolimus MOA

A

Calcineurin inhibitor
Binds to FK506 binding protein
Inhibits T-cell proliferation

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6
Q

Tacrolimus SE

A

⬆️R infections
⬆️R of tumours (skin cancers)

Toxicity - renal failure

Metabolised by CYP450

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7
Q

CYP450 Inhibitors

⬆️drug levels

A

SICKFACES.COM Group

Sodium valproate
Isoniazid
Cimetidine
Ketoconazole

Fluconazole
Alcohol binge
Chloramphenicol
Erythromycin/clarithromycin
Sulphonamides

Ciprofloxacin
Omeprazole
Metronidazole

Grapefruit juice

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8
Q

CYP450 Inducers

⬇️drug levels

A

CRAP GPS

Carbamazepine
Rifampicin
Alcohol (chronic)
Phenytoin
Griseofulvin
Phenobarbitone
Sulphonylureas

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9
Q

Gingival hyperplasia

A

Phenytoin
Ciclosporin
Nifedipine

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10
Q

Increased saliva

A

Clozapine
Neostigmine

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Drug interactions (13 decks)

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