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Drug interactions > Diuretics > Flashcards

Diuretics Flashcards

1
Q

Loop diuretic MOA

A

Blocks NKCC2 channels in thick ascending loop of Henle

Prevent reabsorption of 25% Na+

Reduces renin secretion

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2
Q

Loop diuretic examples

A

Furosemide

Bumetanide

Indapamide

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3
Q

Loop diuretics SE

A

Ototoxicity
Metabolic alkalosis
⬇️K+, Mg2+, PO43-
⬆️Na+
Acidification of urine

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4
Q

Thiazide diuretic examples

A

Bendroflumethiazide
Metolozone (thiazide-like)

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5
Q

Thiazide diuretics MOA

A

Block NaCl cotransporter in DCT

Prevents reabsorption of 10% Na+

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6
Q

Thiazide diuretic SE

A

⬇️K+, Na+, Cl-
⬆️glucose tolerance
⬇️BP
Impotence

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Drug interactions (13 decks)

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