Psych Drugs Flashcards
1
Q
Fluoxetine interactions
A
Tamoxifen (fluoxetine ⬇️s effect)
2
Q
SSRI MOA
A
⬇️presynaptic absorption of serotonin
⬆️extracellular serotonin
3
Q
SSRI SE
A
Appetite and wt changes
Sexual dysfunction
⬆️R of bleeding (inhibit plts)
⬇️Na+ (SIADH)
⬆️QTc
Serotonin syndrome (altered MS, autonomic dysf., neuromuscular abnormalities)
4
Q
SSRI interactions
A
Antiepileptics (⬇️seizure thresh.)
Antidiabetics
Antiplts/anticoags
Carbamazepine (⬇️sertraline)
HIV protease inh (⬇️SSRI)
Lithium (serotonin syn., NMS, QTc⬆️)
MOAI (SS, NMS)
Venlafaxine (QTc⬆️)
Tamoxifen (fluoxetine/paroxetine ⬇️tamoxifen)
