Analgesia Flashcards

1
Q

Cox-2 inhibitor examples

A

Parecoxib
Celecoxib

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2
Q

Cox-2 inhibitor SE

A

Anti inflammatory
Prothrombotic (⬆️R CV events)
CCF exacerbation/HTN

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3
Q

Cox-1 inhibitor SE

A

GI ulceration (⬇️ gastric mucosal pH)
AKI

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4
Q

Cox-1 inhibitor MOA

A

⬇️prostaglandin production —> ⬇️integrity of gastric mucosa

Prevents renal artery dilation

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5
Q

Cox-2 inhibitor MOA

A

⬇️prostaglandin production in response to inflammation

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