Analgesia Flashcards
1
Q
Cox-2 inhibitor examples
A
Parecoxib
Celecoxib
2
Q
Cox-2 inhibitor SE
A
Anti inflammatory
Prothrombotic (⬆️R CV events)
CCF exacerbation/HTN
3
Q
Cox-1 inhibitor SE
A
GI ulceration (⬇️ gastric mucosal pH)
AKI
4
Q
Cox-1 inhibitor MOA
A
⬇️prostaglandin production —> ⬇️integrity of gastric mucosa
Prevents renal artery dilation
5
Q
Cox-2 inhibitor MOA
A
⬇️prostaglandin production in response to inflammation