Rh Blood Group Flashcards
Nomenclatures of the Rh system:
Based on the theory that antigen of the systems were produced by three closely linked set of alleles, each gene was responsible for producing a product (or antigen on the red cells surface)
Fisher-Race (DCE)
Nomenclatures of the Rh system:
Postulated that gene responsible for defining Rh actually produced an agglutinogen that contained a series of blood factors, in which each factor is an antigen recognized by an antibody
Wiener (Rh-Hr)
Nomenclatures of the Rh system:
Number is assigned to each antigen of three Rh system in order of its discovery
Rosenfield (Alpha numeric)
D antigens expressed appear to be complete, but few in number
Genetic weak D
One or more parts of the D antigen is missing
D mosaic or partial D
Position effect or gene interaction effect
C trans
Used to quantitate the number of fetal Rh-positive cells in the mother’s circulation as a result of a fetomaternal hemorrage
Kleihauer-Betke Test or Flow Cytometry