Blood Components And Derivatives (part 2)

Question 1

When there is a specific coagulation factor deficiency where coagulation factors are not available

Answer 1

Fresh frozen plasma

Question 2

Volume of fresh frozen plasma

Answer 2

200 - 260 ml

Question 3

Shelf life of fresh frozen plasma

Answer 3

1 year at -18°C or below

Question 4

Component remaining after cryoprecipitate is prepared

Answer 4

CRYOPOOR PLASMA

Question 5

Cryopoor plasma has minimal concentrations of

Answer 5

Fibrinogen
Factor VIII
vWF

Question 6

Used in patients with hemolytic uremic syndrome, thrombotic thrombocytopenic purpura

Answer 6

CRYOPOOR PLASMA

Question 7

Volume of CRYOPOOR PLASMA

Answer 7

200 mL

Question 8

Shelf life of CRYOPOOR PLASMA

Answer 8

same as FFP 1 year at -18°C or below

Question 9

Derived from FFP

Answer 9

CRYOPRECIPITATE

Question 10

CRYOPRECIPITATE is used for acquired deficiencies of

Answer 10

fibrinogen and factor XIII deficiency

Question 11

Used in vWF and hemophilia A when virus-
inactivated factor concentrates are not available

Answer 11

CRYOPRECIPITATE

Question 12

Volume of CRYOPRECIPITATE

Answer 12

10 - 15 ml

Question 13

Shelf life of CRYOPRECIPITATE

Answer 13

1 year at -18°C or below and 6 hours after thawing

Question 14

Fractionation of pooled donor plasma

Answer 14

FACTOR VIII (LYOPHILIZED)

Question 15

Volume of FACTOR VIII (LYOPHILIZED)

Answer 15

25 ml of sterile diluent for reconstitution

Question 16

Shelf life of FACTOR VIII (LYOPHILIZED)

Answer 16

2 years at 2-8°C

Question 17

Plasma-derived and recombinant proteins are available

Answer 17

Factor IX

Question 18

Factor IX complex:

Answer 18

factors II, VII, IX and other proteins

Question 19

human purified by immunoaffinity chromatography from pooled human plasma contains other traces of proteins

Answer 19

Factor IX

Question 20

Volume of factor IX

Answer 20

25 ml of sterile diluent for reconstitution

Question 21

Shelf life of factor IX

Answer 21

2 years at 2-8°C

Question 22

is used to treat hemophilia B and in patients with inhibitors to factor VIII or IX

Answer 22

Plasma derived factor IX complex

Question 23

ANTITHROMBIN III CONCENTRATE is Prepared from pooled human plasma by

Answer 23

Modified cold ethanol fractionation

Question 24

Treatment or prophylaxis of thrombotic events in patients with congenital antithrombin deficiency (DIC, heparin resistance, sepsis, deep vein
thrombosis, pulmonary embolism)

Answer 24

ANTITHROMBIN III CONCENTRATE

Question 25

Shelf life of ANTITHROMBIN III CONCENTRATE

Answer 25

2 years at 2-8°C

Question 26

May have minimal content of high-molecular
weight vWF

Answer 26

S/D (SOLVENT/DETERGENT) TREATED PLASMA

Question 27

to inactivate lipid- enveloped viruses (HIV, HCV)

Answer 27

S/D (SOLVENT/DETERGENT) TREATED PLASMA

Question 28

Volume of S/D (SOLVENT/DETERGENT) TREATED PLASMA

Answer 28

200 mL

Question 29

Shelf life of S/D (SOLVENT/DETERGENT) TREATED PLASMA

Answer 29

1 year at -18°C

Question 30

Components of albumin

Answer 30

96% albumin, 4% other plasma proteins

Question 31

Albumin is prepared by

Answer 31

Cold Ethan fractionation

Question 32

Volume of albumin

Answer 32

25 - 50 mL

Question 33

Shelf life of albumin

Answer 33

5 years at 2-10°C

Question 34

PLASMA PROTEIN FRACTION contains

Answer 34

83% albumin and 17% globulin

Question 35

Prepared from pooled human plasma by cold ethanol fractionation

Question 36

It has gained acceptance in the treatment of
Guillain-Barre’s syndrome

Answer 36

IMMUNE GLOBULIN, INTRAVENOUS

Question 37

IgG anti-Rho full dose and minídose

Answer 37

full dose is 300ug, minidose is 50ug

Question 38

Component of FIBRIN SEALANT

Answer 38

Fibrinogen,
human thrombin,
aprotinin
calcium chloride

Question 39

Sealing anastomoses, treatment of spleen injuries

Answer 39

FIBRIN SEALANT

Question 40

Adjunct to hemostasis in cardiopulmonary bypass surgery

Answer 40

FIBRIN SEALANT