Blood Components and Plasma Derivatives

Question 1

Whole blood

Answer 1

Symptomatic anemia with large-volume deficit

Question 2

Red blood cells: RBCs (adenine-saline added), RBC pheresis

Answer 2

Symptomatic anemia

Question 3

Red blood cells: deglycerolized, washed

Answer 3

Severe allergic reactions
Rare donors

Question 4

Red blood cells: leukocyte-reduced

Answer 4

Symptomatic anemia
Febrile reactions due to leukocyte antibodies
Reduce CMV transmission
Reduce HLA alloimmunization

Question 5

Platelets: platelets pooled

Answer 5

Bleeding due to thrombocytopenia or platelet function abnormality
Prevention of bleeding from marrow hypoplasia

Question 6

Platelets pheresis

Answer 6

Bleeding due to thrombocytopenia or platelet function abnormality
Prevention of bleeding from marrow hypoplasia
Crossmatched or HLA-matched

Question 7

Platelets or platelets pheresis, leukocyte-reduced

Answer 7

see Platelets
Prevention of febrile reactions and HLA-alloimmunization

Question 8

Granulocytes pheresis

Answer 8

Neutropenia with infection unresponsive to appropriate antibiotics

Question 9

Plasma

Answer 9

Deficiency of labile and stable plasma coagulation factors; TTP

Question 10

Composition of plasma

Answer 10

All coagulation factors
ADAMTS 13

Question 11

Cryoprecipitate pooled

Answer 11

Hypofibrinogenemia
Factor XIIl deficiency

Question 12

Composition of Cryoprecipitate pooled

Answer 12

Fibrinogen, VWF, factors VIII and XIII