Respiratory12

Question 1

What are the clinical uses for 1st generation H1 blockers?

Answer 1

Allergy
Motion sickness
Sleep aid

Question 2

What are the clinical uses for 2nd generation H1 blockers?

Answer 2

Allergy

Question 3

What are the side effects of the 1st generation H1 blockers?

Answer 3

Sedation
Antimuscarinic
anti-a-adrenergic

Question 4

What is the benefit of 2nd generation H1 blockers over 1st generation?

Answer 4

Far less sedating; DEcreased entry into CNS

Question 5

Diphenhydramine

Answer 5

1st generation H1 blocker

Question 6

Loratadine

Answer 6

2nd generation H1 blocker

Question 7

Fexofenadine

Answer 7

2nd generation H1 blocker

Question 8

Chlorpheniramine

Answer 8

1st generation H1 blocker

Question 9

Desloratadine

Answer 9

2nd generation H1 blocker

Question 10

Dimnenhydrinate

Answer 10

1st generation H1 blocker

Question 11

Cetirizine

Answer 11

2nd generation H1 blocker

Question 12

What are the 1st generation H1 blockers?

Answer 12

*contain “-en/-ine” or “-en/-ate”

Diphenhydramine
Dimenhydrinate
Chlorpheniramine

Question 13

What are the 2nd generation H1 blockers?

Answer 13

“typically end in “-adine”

Loratadine
Fexofenadine
Desloratadine
Cetirizine