Respiratory1 Flashcards

Anatomy

1
Q

What are the two zones of the respiratory tree?

A

Conducting zone

Respiratory zone

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2
Q

What does the large airways consist of in the conducting zone?

A

Nose
Pharynx
Trachea
Bronchi

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3
Q

What does the Small airways consist of in the conducting zone?

A

Bronchioles

Terminal bronchioles

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4
Q

What is the function of the conducting zone?

A

Warms, Humidifies and Filters Air

*DOES NOT participate in gas exchange

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5
Q

What extends to the end of the bronchi?

A

Cartilage

Goblet cells

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6
Q

What extends to the end of the terminal bronchioles?

A

Psuedostratified ciliated columnar cells
- beat mucus up and out of lungs
Smooth Muscle of the airway walls
- Sparse beyond this point

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7
Q

What makes up the Respiratory zone?

A

Lung parenchyma; consisting of:

  • Respiratory brionchioles
  • Alveolar ducts
  • Alveoli
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8
Q

What types of epithelia make up the respiratory zone?

A

Cuboidal cells in respiratory bronchioles
Simple squamous cells up to alveoli

  • NO CILIA
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9
Q

What are the 3 types of pneumocytes?

A

Type I cells
Type II cells
Clara cells

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10
Q

Describe type I pneumocytes.

A
  • 97% of alveolar surfaces
  • Line the alveoli
  • Squamous; thin for optimal gas diffusion
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11
Q

What cells secrete pulmonary surfactant?

A

Type II pneumocytes

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12
Q

Function of pulmonary surfactant.

A

DEcrease Alveolar Surface Tension

Prevent alveolar collapse (atelectasis)

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13
Q

What cells proliferate during lung damage?

A

Type II pneumocytes

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14
Q

Describe Clara cells.

A

Nonciliated; Columnar w/ secretory granules
Secrete component of Surfactant
Degrade toxins
Act as reserve cell

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15
Q

What is the equation for Collapsing Pressure (P)?

A

P = 2(surface tension)/radius

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16
Q

What is the Law of Leplace state?

A

Alveoli have INcreased tendency to collapse on Expiration as Radius DEcreases

17
Q

What is dipalmitoylphosphatidylcholine?

A

most importan Lecithins, which makes up pulmonary surfactant

18
Q

When does surfactant synthesis begin?

When are mature levels reached?

A

Week 26 of gestation

*Mature levels are not acheived until around week 35

19
Q

A lecithin-to-sphingomyelin ration > ___ in amniotic fluid indicates fetal lung Maturity.

A

> 2.0 (lectithin:sphingomyelin)