Respiratory Tract Infections Flashcards

1
Q

What are the main causes of respiratory tract infections (RTIs)?

A

Viruses (90% of upper RTIs, 30% of lower RTIs), bacteria, and rarely fungi

Common viral causes include rhinoviruses, RSV, influenza, and coronaviruses. Bacterial causes include Streptococcus pneumoniae and Mycobacterium tuberculosis.

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2
Q

What are some examples of upper respiratory tract infections?

A
  • Common cold
  • Sinusitis
  • Tonsillitis
  • Laryngitis
  • Pharyngitis
  • Otitis media
  • Bronchitis
  • Bronchiolitis

Upper RTIs are typically less severe but can lead to complications.

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3
Q

What are some examples of lower respiratory tract infections?

A
  • Pneumonia
  • Lung abscess
  • Pulmonary TB

Lower RTIs can be more severe and are a major cause of hospital admissions.

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4
Q

What is the primary mode of transmission for respiratory infections?

A

Air droplets transmission and direct contact

Infection can spread when a person coughs or sneezes near you or when touching infected surfaces.

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5
Q

What are the key defenses of the respiratory tract?

A
  • Nasal cavity hairs & mucus
  • Cilia
  • Cough reflex
  • Normal flora

These defenses help to trap and expel pathogens from the respiratory system.

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6
Q

What immune responses are initiated following respiratory tract infection?

A
  • Innate immune responses
  • First order cytokines
  • Second order cytokines

These responses involve the activation of immune cells to clear pathogens and facilitate tissue repair.

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7
Q

What are common signs and symptoms of respiratory tract infections?

A
  • Cough
  • Phlegm production
  • Sneezing
  • Sore throat
  • Headaches
  • Muscle aches
  • High temperature
  • Breathlessness

Symptoms can vary depending on the severity and type of infection.

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8
Q

What risk factors increase susceptibility to RTIs?

A
  • Contact with infected individuals
  • Smoking
  • Alcoholism
  • Immunocompromised status
  • Long-term health conditions
  • Age (elderly/very young)

These factors can compromise the immune system and respiratory defenses.

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9
Q

What are the components of a physical examination for diagnosing RTIs?

A
  • Listening to lung sounds
  • Throat examination
  • Checking swollen glands
  • Taking temperature
  • Assessing pulse and blood pressure

A thorough examination is essential for accurate diagnosis.

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10
Q

What investigations may be necessary for diagnosing RTIs?

A
  • Chest X-ray
  • Blood tests (CRP, WBCs)
  • Sputum culture
  • Nasal & throat swabs
  • Urinary antigen tests

These tests help identify the causative agents and assess severity.

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11
Q

What is the CURB-65 score used for?

A

Assessing mortality risk in pneumonia patients

It considers confusion, urea levels, respiratory rate, and blood pressure.

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12
Q

What are some red flags indicating severe respiratory infection?

A
  • Cough > 3 weeks
  • Very high temperature
  • Pleuritic chest pain
  • Haemoptysis
  • Symptoms worsening

These signs warrant immediate medical attention.

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13
Q

What is the primary treatment approach for most RTIs?

A

Symptomatic relief and self-care measures

Most RTIs are viral and self-limiting; treatments focus on alleviating symptoms.

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14
Q

Fill in the blank: Annual _______ vaccination is recommended for those at higher risk for respiratory infections.

A

[flu]

Vaccinations help reduce the risk of severe respiratory infections.

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15
Q

True or False: Antibiotics are indicated for viral respiratory infections.

A

False

Antibiotics are ineffective against viruses and should be used only for bacterial infections.

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16
Q

What is antimicrobial stewardship?

A

Using antibiotics only when necessary and appropriate

This approach aims to reduce antibiotic resistance and protect patient safety.

17
Q

What are some self-care measures for RTIs?

A
  • Rest and hydration
  • Hot lemon and honey drink
  • Gargling with warm salty water
  • Using extra pillows while sleeping

These measures can help alleviate symptoms and promote recovery.

18
Q

What is the role of interferon in respiratory infections?

A

It helps in pathogen clearance and initiates immune responses

Interferons are crucial in fighting viral infections.