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ANHB1102 > Respiratory System > Flashcards

Respiratory System Flashcards

1
Q

What is tidal volume?

A

The amount of air moved during quiet breathing

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2
Q

What is the thickness of the respiratory membrane?

A

0.5 micrometers

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3
Q

What are the requirements for the respiratory membrane?

A
  • thin
  • moist
  • large blood supply
  • large surface area
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4
Q

How many pulmonary lobes are in the right lung?

A

3

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5
Q

How many pulmonary lobes are in the left lung?

A

2

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6
Q

What are the functions of the respiratory system?

A
  • moves air in and out of the body for O2 and CO2 exchange
  • olfaction
  • non-specific defence against pathogens
  • acid-base balance
  • vocal communication
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7
Q

What is the conducting zone?

A

Conducts air to the respiratory zone

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8
Q

What is the respiratory zone?

A

The area in which gas exchange occurs

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9
Q

What are the three types of cells in the alveoli?

A
  • type 1
  • type 2
  • alveolar macrophages
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10
Q

What do type 1 alveolar cells do?

A
  • simple squamous epithelium

- has exchange

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11
Q

What do type 2 alveolar cells do?

A
  • maintain type 1 cells

- produce surfactant that prevents the alveoli from collapsing when we exhale

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12
Q

What do alveolar macrophages do?

A
  • digest pathogens that reach the alveoli

- once they reach capacity they move up the conducting zone and get trapped in the mucociliary escalator

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13
Q

What makes up the blood/gas barrier?

A
  • simple squamous epithelium of the type 1 alveolar cells
  • simple squamous epithelium of the endothelial cells
  • shared basement membrane
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14
Q

What are some characteristics of the blood/gas barrier?

A
  • one of the thinnest surfaces in the body

- basement membrane contains collagen

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15
Q

What is Boyle’s law?

A

At a constant temperature, the pressure of a given quantity of gas is inversely proportional to its volume

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16
Q

What is Charles’s law?

A

At a constant pressure, the volume of a gas is directly proportional to its absolute temperature

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17
Q

How does the nasal cavity modify air entering the lungs?

A
  • cleans
  • moistens
  • warms
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18
Q

Nasal cavity: cleans

A

Entry: hairs
Within: coli and mucus

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19
Q

Nasal cavity: moistens

A

Glands and goblet cells

Transduction

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20
Q

Nasal cavity: warms

A

Blood sinusoids: blood vessels that occupy the CT of underlying epithelium

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21
Q

Embryological development

A

Derived from ectoderm

By 8 weeks resemble an adult structure

22
Q

What are the sections of the pharynx?

A

Nasopharynx, oropharynx and larygopharynx

23
Q

Nasopharynx epithelium

A

Respiratory epithelium

24
Q

Larygopharynx epithelium

A

Non keratinised stratified squamous epithelium

25
Q

What is the primary function of the larynx?

A

Protection of the airway

Secondary: phonation

26
Q

What does the epiglottis do?

A

When swallowing bends backwards and covers the larynx

27
Q

What type of cartilage is around the trachea?

A

Hyalin

28
Q

Why are there gaps in the cartilage?

A

Allows room for esophagus to expand when food is swallowed

29
Q

How does smoking affect the respiratory system?

A
  • causes paralysis of cilia function

- overtime causes metaplasia - changes to stratified squamous epithelium

30
Q

Main bronchi

A

Go into each of the lungs

31
Q

Lobal bronchi

A

Go into each of the lobes

32
Q

Segmental bronchi

A

Go into bronchopulmonary segments

33
Q

Bronchi epithelium/cartilage/muscle

A
  • cartilage

- pseudostratified columnar ciliated

34
Q

Bronchioles epithelium/cartilage/muscle

A
  • smooth muscle

- ciliated pseudostratified epithelium to simple ciliated columnar

35
Q

What are terminal bronchioles?

A
  • final branches of conducting zone

- ciliated columnar epithelium (no goblet cells)

36
Q

Where do the lungs receive blood from?

A
  • pulmonary arteries (98%)

- bronchial arteries (2%)

37
Q

Do alveolar ducts have smooth muscle?

A

Yes

38
Q

What stimulates the diaphragm?

A

Phrenic nerve

39
Q

What does the diaphragm move?

A

Moves itself inferiority

Pushes outward on sternum and ribs

40
Q

What is normal blood pH?

A

7.35-7.45

41
Q

Explain why the interpleural pressure is negative

A
  • due to their elasticity, at the end of normal expiration the chest wall with its pleura tends to expand outward whereas as the lungs with their pleura tend to recoil inwards
  • as the chest wall and lungs are pulling in opposite direction, a slightly negative pressure is generated in the interpleural space
42
Q

Explain how changes in the position of the diaphragm and chest diameter influence changes in volume and pressure that contribute to inflation of the lungs (refer to Boyle’s law)

A
  • when the diaphragm contracts inferiority and the ribs move up and out during inspiration, the parietal pleura follows
  • as the visceral layer clings to the parietal layer the lungs expand
  • due to the increase in volume, the internal pressure of the lungs relative to the outside drops (Boyle’s law) and air flows in
43
Q

Explain how the warming of the air inhaled by structures su h S the nasal conchae contributes to inflation of the lungs

A
  • according to Charles’s law, the volume of a gas is directly proportional to its absolute temperature
  • by the time air reaches the alveoli, it has been warmed to 37 degrees
  • if the air outside is cooler than this, then the inhaled volume will increase due to thermal expansion, further contributing to lung expansion
44
Q

What is the role of surfactant?

A
  • for gas exchange to occur alveoli must stay moist
  • this creates a problem as during exhalation the alveoli would stick together like pieces of wet paper making them difficult to rein flame
  • surfactant coats the alveoli and smallest bronchioles to prevent them from collapsing during exhalation
45
Q

Why does residual volume always occur?

A

Because the lungs are stuck to the chest wall via pleura

46
Q

Where does gas exchange first occur?

A

Respiratory bronchiole

47
Q

Where does smooth muscle disappear?

A

Alveolar duct

48
Q

Where does simple squamous epithelium first appear?

A

Respiratory bronchiole

49
Q

Where are is the ventral respiratory group?

A
  • medulla oblongata
  • contains I and E neurons
  • E neurons cause the diaphragm to contract, I inhibit E neurons
50
Q

How many times do you breath per minute?

A

12

51
Q

Where are the peripheral chemo receptors?

A

Aortic and carotid bodies

52
Q

What does the dorsal respiratory group alter?

A

Rat and depth of breathing

ANHB1102 (11 decks)

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