Respiratory system Flashcards
Is asthma, reversible
Yes
When do you review treatment?
Review every three months, stepping down, reduce ICS dose by 25 to 50% each time
Lama
Example
Tiotropium
Should you initiate LABA in rapidly deteriorating asthma?
No
What should explicit be stated?
State dose frequency and max dose in 24 hours
What is it important to remember with zafiruklast
Liver, toxicity
When is theophylline concentration increased?
Heart, failure, liver, impairment, viral infections, elderly, enzyme, inhibitors
When is theophylline concentration decreased?
Smoking alcohol, enzyme inducer i
How to treat an asthma
Salbutamol by a large volume spacer 2 to 10 past every 10 to 20 minutes or when required or salbutamol/tribute to lean nebuliser oxygen to run if possible. Every 20 to 30 minutes are in required. If symptoms persist after 1530 minutes call 999. Repeat above an ad nebuliser ipratropium bromide plus in all cases at prednisolone or Ivy hydrocortisone children under 12 to 3 days for adults at least five days 40-50mg once daily
When is there a risk of angle-closure glaucoma?
Nebulised ipratropium
Hydroxyzine CA
QT prolongation drugs, that cardiovascular disease, family history
Ca for mucolytics
Active peptic ulcer mucolytics disrupt gastric mucosa
Gradual withdrawal should be considered for corticosteroid withdrawal
> 40mg oral prednisone for more than one week
Repeated evening corticosteroids
Repeated courses
Long term therapy
Asthma excaberations dose
40mg for 5 days
Copd excaberations
Prednisolone 30mg for 7 -14days
