Endocrine Flashcards

1
Q

What is nephrogenic diabetes?

A

The kidneys do not respond to ADH

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2
Q

What is cranial diabetes?

A

The hypothalamus does not make enough ADH

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3
Q

What is the side effect of desmopressin?

A

Hyponatraemia convulsions

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4
Q

If fluid restriction, does not correct hyponatraemia in syndrome of inappropriate antidiuretic hormone secretion, then what can you use?

A

Democycline, blocks, renal tubular effect of ADH,
tolvaotan
vasopressin antagonist
Avoid rapid correction of hyponatraemia causes, osmotic, demyelination of new run serious CNS effects

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5
Q

High mineralcorticosteroid activity means

A

Fluid retention

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6
Q

Glucortucoid side effects I

A

Diabetes, osteoporosis peptic, ulcers, dyspepsia
Muscle wasting
Psychiatric reactions, infections, adrenal, suppression, glucoma

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7
Q

Why is it important to steroids in the morning?

A

Single dose in the mooning suppressive action on cortisol secretion is the least in the morning 

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8
Q

What do you give gesstational diabetes in women intolerant of Metformin, and do not want insulin

A

Glibenclamide from 11 weeks gestation after organogenesis

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9
Q

When are insulin requirements increased?

A

Infections, stress, puberty and presidency

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10
Q

Insulin requirements decreased

A

Unicorn disorders, Addison is coeliac disease

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11
Q

The 4 R’s

A

Right insulin right dose, right time right route

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12
Q

What antagonises hypoglycaemic a effect of insulin

A

Corticosteroids oral contraceptive diuretics

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13
Q

Metformin, MOa

A

Decrease liver gluconeogenesis and increases peripheral use

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14
Q

Pioglitazone more of action

A

Reduces peripheral resistance only continue, if Hba wants to produce by 0.5% within six months.

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15
Q

Go to thousands, SGL2 inhibitors more action

A

Inhibit, sodium, glucose ” transporter in the renal proximal, tubule to reduce glucose reabsorption and increase urinary excretion

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16
Q

DPP for inhibitors mode of action

A

DPP for breakdown hormone in creating which is made by the court in response to food to increase into the situation and lower Glucagon secretion

17
Q

GLP, one agonist mode of action

A

Binds to an activated GLP, one receptors to increase into integration, suppress GlucaGen situation and slows gastric emptying

18
Q

Hypertension complications with & without complications

A

140/80, without complications with complication to 130/80

19
Q

How to treat hypoglycaemia in community

A

10 to 20 g of glucose if necessary. Repeat after 10 to 15 minutes. Coca-Cola hundred to 200 mL, Lucozade energy original 55, 200 mL sugar lumps to 86 sugar, 2 to 4 teaspoons Ribena 19 miles to be diluted.

20
Q

How is sulphonyurea hypoglycaemia treated?

A

Always in hospital as it can persist for hours

21
Q

What is raloxifene used for?

A

Secondary prevention and treatment for vertigo factors in postmenopausal osteoporosis

22
Q

What is teriparatide used for

A

Use for treatment of menopausal osteoporosis

23
Q

Does linagliptin require dose adjustment in renal impairment

A

No

24
Q

When is dapagliflozin contra indiacted

A

<60

25
Q

Will pregnant women need to take more levothyroxine when they are pregnant?

A

Yes

26
Q

Humilin I

A

Intermediate

27
Q

Humilin , S

A

Rapid acting

28
Q

Levemir

A

Long acting

29
Q

What is ottos externa can be triggered by?

A

Pseudomonas aeruginosa