Respiratory System Flashcards
Inhalation and exhalation are also referred to as what?
Inspiration and expiration
What makes up 80-90% of alveoli cells?
Type I cells
Which alveoli cells are the site of gas exchange?
Type I
Surfactant is made by what type of cells?
Type II alveoli cells
Surfactant is composed of what?
Phospholipids and protein
Why do premature babies experience respiratory distress?
Not enough surfactant
What stimulates surfactant productions?
Steroids
Palv refers to what?
Pressure in the lungs
What does Patm refer to?
Atmospheric pressure
Patm is set to what value by default?
0
What does Pip refer to?
Intrapleural pressure, suctions lungs to chest wall
Pip is positive or negative?
Negative
Ptp is the difference between what two pressures?
Palv-Pip
During which phase of the respiratory cycle is the diaphragm pushed down?
Inhalation
When is Pip the most negative?
Peak of inhalation
When is Ptp the highest?
Peak of inhalation
The diaphragm relaxes during which stage of the respiratory cycle?
Exhalation
The external intercostals are associated with inhalation or exhalation?
Inhalation
The internal intercostals are associated with forced exhalation or inhalation?
Forced exhalation
Which muscles are associated with passive exhalation?
Diaphragm
What is lung compliance?
Ability of lungs to return to normal after stretching
Change in volume/Change in Ptp refers to what?
Compliance
Low compliance in the lungs is associated with what?
Fibrosis
What is the level of lung compliance in emphysema?
High
How is fibrosis associated with pulmonary hypertension?
Fibrosis can compress the lung capillaries
Increased tidal volume occurs in fibrosis or empysema?
Fibrosis
What is emphysema?
Floppy lung, lung can inflate easily but doesn’t deflate easily
What is the cause of emphysema?
Smoking, air pollution
Self destructing alveola occurs in which pathology?
Emphysema
Hypoxia refers to what?
Low oxygen - decreased area for gas exchange
Hypoxia occurs in which pathology?
Emphysema
What is a treatment for emphysema?
Bronchodilators, inhaled steroids
What is tidal volume (TV)?
Regular volume (inhale, exhale) at rest
What is inspiratory reserve volume (IRV)?
Extra lung volume for deep inhalation
What is expiratory reserve volume (ERV)?
Additional lung volume for deep exhalation
What is RV (residual volume)?
Extra air in the lungs, always remains
What is vital capacity (VC)?
ERV + IRV + TV
What is total lung capacity (TLC)?
RV + VC
What is the difference between TLC and VC?
TLC is the whole lung capacity, whereas VC is the usable lung capacity
What is FEV1/FVC ratio used for?
Ratio of lung functioning
How do CO2 and O2 flow in the lungs?
O2 travels from alveoli to blood, CO2 travels from blood to the alveoli
How do CO2 and O2 flow in tissues?
O2 flows from blood to tissue, CO2 flows from tissue to blood
What is the arterial PO2?
100mmHg
What is the PO2 in venous circulation?
40mmHg
Hyperventilation is an increase or decrease in CO2 levels?
Decrease of CO2 compared to production
Hypoventilation is an increase or decrease of CO2?
Increase of CO2 production, not exhaling enough out
How does increased pH shift the oxygen-hemoglobin dissociation curve?
to the right
Increased temperature shifts the oxygen-hemoglobin dissociation curve how?
to the right
The pneumotaxic center and apneustic center are located in the pons or the medulla?
The pons
The DRG and VRG are located in the pons or the medulla?
Medulla
What function does the DRG serves?
Fires to cause inhalation
What function does the VRG serve?
Fires to cause exhalation
Which intercostal muscle does the DRG innervate?
The external intercostal
Which intercostal does the VRG innervate?
Internal intercostal
The pre-Botzinger complex is associated with the VRG or the DRG?
The VRG
What is the function of the pre-Botzinger complex?
Controls rhythm, sets basal respiratory rate
What are the 2 types of chemoreceptors?
Peripheral and central
Where are the peripheral chemoreceptors located?
In the aortic and carotid bodies
Where are central chemoreceptors located?
In the medulla oblongata
Which gas is the central chemoreceptor not sensitive to?
Oxygen
What does the central chemoreceptor do?
Monitor changes in H+ in cerebrospinal fluid
PO2 under 60mmHg stimulates which receptor?
The peripheral chemoreceptors
Hyperventilation is used to compensate for an increase or decrease in H+?
Increase