respiratory quiz Flashcards

1
Q

Forced expiratory volume (FEV)

A
  • a test which limits the time a subject has to expel vital capacity air.
  • Normal 97% in 3 sec
  • Reduced in restrictive pulmonary diseases.
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2
Q

Maximal voluntary ventilation (MVV)

A
  • measures both volume and flow rates to assess overall pulmonary ventilation function
  • pt inspires and expires and deeply and fast as possible while tidal volume and RR are measured
  • look at average volume/respiratory cycle.
  • tends to be reduced in both restrictive and obstructive diseases
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3
Q

spirometer

A

the instrument used to measure breath

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4
Q

spirogram

A

the record of volume change versus time of breath

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5
Q

tidal volume

A
  • the volume of air inspired or expired during a single normal breath
  • ~500mL at rest
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6
Q

Inspiratory reserve volume (IRV)

A
  • the volume of air that can be maximally inhaled after tidal inspiration
  • resting IRV is male: 3300mL
  • Female: 1900mL
  • IRV decreases with
    • increased age
    • decreased compliance
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7
Q

Expiratory reserve volume (ERV)

A
  • the volume of air that can be maximally expired after tidal expiration
  • males: 1000mL
  • Females: 700mL
  • ERV decreases with
    • increased age
    • decreased lung elasticity
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8
Q

Residual volume (RV)

A
  • the volume of gas remaining in the lungs at the end of maximal expiration
  • does not change with exercise
  • Male: 1200ml
  • Female: 1100ml
  • Residual increases with
    • increased age
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9
Q

Inspiratory capacity (IC) =

A

Tidal Volume (TV) + inspiratory reserve volume (IRV)

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10
Q

Expiratory capacity (EC) =

A

Tidal volume (TV) + expiratory reserve volume (ERV)

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11
Q

Functional residual capacity (FRC) =

A

expiratory reserve volume + residual volume

ERV + RV

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12
Q

Vital capacity (VC) =

A
  • inspiratory reserve volume + Tidal volume + expiratory reserve volume
  • IRV + TV + ERV
  • Sum of the three primary lung volumes
  • Vital capacity decreases with
    • age
    • restrictive disorders
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13
Q

Total lung capacity (TLC) =

A

inspiratory reserve volume + tidal volume + expiratory reserve volume + residual volume

IRV + TV + ERV + RV

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14
Q

Influencing factors on the rate of diffusion

A
  • partial pressure - directly
  • surface area - directly
  • thickness of the membrane - indiretly
  • solubility of gas - direclty
    • CO2 is 20x more soluble than O2
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15
Q

Alveolar ventilation of the lungs

Ideal ratio vs. Real ratio

Why?

A
  • Ideal is 1:1
  • Real is 0.8-0.9:1
  • Regional airflow assumes all parts of the lungs are equally ventilated and perfused.
    • Reality is the base has greater alvealar ventilation due to a number of factors
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16
Q

Influencing Factors for ventilation-perfusion ratios: air flow to the base

A
  • Larger transpulmonary pressure across the lung base
  • Increased airway resistance in the upper passages
  • Alveolar O2 and CO2 levels
    • High CO2 cause decreased blood flow (high levels cause vasoconstriction and low blood flow)
    • High O2 cause the greates blood flow (high levels cause vasodilation and increased blood flow)
  • Gravity
    • Upright position keeps a larger percentage of blood in the lung base
17
Q

Boyle’s Law

A

PV = K

18
Q

Dalton’s law

A

Pressure = P1 + P2 + P3 + etc

19
Q

Muscles of inspiration

A

external intercostals, diaphragm

20
Q

Muscles of expiration

A
  • Normal expiration = relaxation of inspiratory muscles
  • Forced expiration = internal intercostals and rectus abdominus
21
Q

Compliance is

A
  • CL = V/P
  • the measurement of lung distensibility or the ease of stretching
  • NOTE: compliance refers ONLY to INSPIRATION!
22
Q

Compliance curve shows

A
  • the ease of inflatability against averages
    • steep slope = easily inflatable
    • flat slope = difficult to inflate
23
Q

Calculation for the transpulmonary pressure

A

P(Transpulmonary) = P(alveolar) - P(interplural)

24
Q

Calculation for pulmonary ventilation

A

Pulmonary ventilation = TV x RR

25
Q

Calculation for alveolar ventilation

A

Alveolar ventilation = (TV - ADS) x RR

26
Q

Gas exhange is _______ during inspiration and expiration

A

constant

27
Q

It takes _____ to replace all the air in the alveolus

A

90 seconds

28
Q

Calculating O2 carrying capacity

A

Carrying capacity = gm Hb/dl x 1.34 ml O2/gm Hb

ex: Carrying capacity = 15 g/dl x 1.34 ml O2/gm Hb

= 20.1 ml O2/dl

or 20 vol%

29
Q

The body requires what rate of blood flow for delivery of sufficient oxygen?

A

5 Liters

30
Q

The most powerful chemical influence on the regulation of alveolar ventilation is

A

PCO2 in the systemic arterial blood

31
Q

The greates partial pressure of carbon dioxide is in the

A

intracellular fluid

32
Q

According to the dissociation curve, oxyhemoglobin saturation is effected PCO2, pH, H+, and Temp in the following manner.

A
  • PCO2 : directly
  • pH :indirectly (increase = decrease O2)
  • H+: directly
  • Temp: directly
33
Q

The Hering-Breuer reflex…

A

prevents overstretch by inhibiting further inspiration

34
Q

The Bohr Effect states

A

as H+ is loaded onto Hb, O2 is bumped off

35
Q

The Haldane effect states

A

An increase in CO2 production causes the Hb to accept more CO2

thus limiting the amount of free CO2 in blood circulation

36
Q

The distribution of CO2 in circulation is

A
  • 10% Dissolved in blood
  • 20% in Carbaminohemoglobin
  • 70% in Bicarbonate
37
Q

The distribution of O2 in the blood

A
  • 1.5% dissolved in the blood
  • 98.5% bound in oxyhemoglobin
38
Q
A