Respiratory histology Flashcards

1
Q

what does the conducting portion of respiratory tract do

A

Warms, filters and humidifies air

  • Transmit to respiratory portion
  • NO gas exchange = “Anatomic Dead Space
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2
Q

what makes up conduction portion of tract?

A

Nasal Cavity, Paranasal sinuses, Nasopharynx,
Trachea

  • Primary, Secondary, & Tertiary Bronchi
  • Bronchioles, Terminal Bronchioles
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3
Q

what does the respiratory portion of respiratory tract do

A

Pass air to alveoli for gas exchange

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4
Q

what makes up respiratory portion of respiratory tract?

A

Respiratory Bronchioles, Alveolar ducts, Alveolar Sacs

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5
Q

what type of cells make up vocal folds?

A

Nonkeratinized stratified squamous epi

•Protect mucosa from abrasions

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6
Q

what type of cells make up respiratory epithelium?

A

Pseudostratified ciliated columnar epithelium

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7
Q

what does respiratory epithelium do?

A
  • Protect airway via mucus production

* Transport mucus up and out of respiratory tract via cilia

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8
Q

name cell layers of respiratory epithelium in order from top to down

A

ciliated

goblet

basal

lamina propria

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9
Q

what type of cells are goblet cells and what do they do?

A

Modified columnar epithelial cells that synthesize & secrete mucus

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10
Q

what are the four layers of the trachea, top to down?

A

mucosa

submucosa

cartilaginous

adventitia

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11
Q

what does the epithelium of the trachea contain?

A

Psuedo-stratifiedcolumnar ciliated

Numerous goblet cells

Elastic, fiber-rich lamina propria

BALT

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12
Q

what does the adventitia of the trachea contain?

A

trachialis m

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13
Q

what does the epithelium of the bronchi contain?

A

psuedo-stratifiedcolumnar ciliated

Cells shorter in height –transition to cuboidal

Fewer goblet cells

Increased elastic fibers inlamina propria

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14
Q

what does the epithelium of the bronchiole contain?

A

Large:simpleciliated columnarSmall: simplecuboidal

Few goblet cellsClubcells

Increased elastic fibers

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15
Q

what are club cells, where are they located?

A

Non-ciliated, dome-shaped cells

  • Secrete a lipoprotein that prevents luminal adhesion w/airway collapse (during expiration)
  • Detoxification of inhaled materials
  • Secrete antimicrobial peptides

terminal bronchioles

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16
Q

describe epithelia of respiratory bronchioles

A

Simplecuboidal epi w/ Club cells

elastic fibers

17
Q

what is so special about respiratory bronchioles?

A

Mucosa contain openings to alveoli –where gas exchange occurs

18
Q

what are alveolar sacs?

A

2+ clusters of alveoli

19
Q

what are Alveolar rings?

A

aggregates of smooth muscle, collagen & elastic fibers, that form rings around alveolar ducts

20
Q

what kind of epithelium is located in alveoli?

A

Simple Squamous epithelium

21
Q

alveoli are lined by what kind of cells?

A

Pneumocytes

22
Q

type 1 pneumocytes are used for what?

A

gas exchange

23
Q

type 2 pneumocytes are used for what?

A

Secrete surfactant,reduces surface tension within alveoli, preventing collapse during respiration

24
Q

parietal and visceral pleura are covered with what?

A

mesothelium

25
Q

parietal and visceral pleura are underlined with what?

A

fibrous tissues of collagen & elastin fibers

Contains extensive lymphatic vessels

26
Q

Blood-Air Barrier is composed of what?

A

3 components

2-3 highly attenuated, thin cells lining the alveolus

Fused basal laminae of these cells and the endothelial cells of the capillaries

Capillary endothelial cells

27
Q

what is asthma caused by?

A

Chronic inflammatory disease involving the airways

Sudden constriction of smooth muscle in bronchioles

Infiltration of bronchiolar wall by eosinophils, lymphocytes, & mast cells

28
Q

what is emphysema caused by?

A

Permanent enlargement of air spaces distal to terminal bronchiole

Chronic obstruction of airflow due to narrowing of bronchioles

Accompanied by destruction of alveolar walls

29
Q

what is pneumonia caused by?

A

Inflammation of lung tissue

Air spaces are filled with exudate containing WBCs (mainly neutrophils), RBCs, & fibrin

30
Q

Red hepatization stage of pneumonia looks like what?

A

looks like Liver