cardiac cycle and sounds Flashcards
describe phase 4 of fast action potential?
phase 4: rest
Na,K, Ca channels are closed
cell is at resting potential
do cardiac myocytes have many funny sodium channels?
no, can’t really use them to depolarize
describe phase 0 of fast action potential?
rapid upsweep
voltage gates Na+ channels open
cell depolarizes
describe phase 1 of fast action potential?
initial repolarization
sodium channels inactivated, no Na+ enters
voltage gate k+ channels open, potassium can leave
describe phase 2 of fast action potential?
repolarization is interrupted
voltage gates Ca chanels open, calcium enters muscle cell
potassium continues to leave cell
membrane potential stabilizes at positive potential
describe phase 3 of fast action potential?
voltage gated calcium channels close
K+ channels remain open
repolarizaion completed
describe order of fast action potential phases
4,0,2,3
what cells does slow action potential occur in?
cells of conduction pathways
SA and AV nodes
describe phase 4 of slow action potential?
steady depolarization
opening of funny sodium channels
how can we alter heart rate? what part of the heart has most of these channels
how fast funny sodium channels open, SA node has the most of these channels!
thats why its the pacemaker
AV node is the backupp
describe phase 0 of slow action potential?
what is special about this?
calcium influx causes depolarization
influx is slower than Na, depolarization takes shorter amount of time
does not get as positive as in skeletal tissue
describe phase 1 of slow action potential?
initial repolarization
where is slow action potential phase 1 and phase 2 not found?
SA and AV nodal tissue
describe phase 2 of slow action potential?
calcium enters cell, allows for contraction
describe phase 3 of slow action potential?
repolarization
efflux of K+
what is P in an ECG?
atrial depolarization initiated by SA node depolarization
what is QRS in an ECG?
phase 0 depolarizations of ventricular myocytes
what is T wave in an ECG?
ventricular repolarization
Relevance of PR interval?
begin at P wave, ends at beginning of QRS wave
time it takes for depolarization to pass from atria to ventricles via AV node
what does PR interval represent, what happens if there is damage?
slow conduction velocity of AV node
damage to AV node means PR interval is prolonged