Respiratory: Gas Exchange Flashcards

1
Q

What is pulmonary ventilation?

A

The volume of air breathed in and out per minute

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2
Q

What is alveolar ventilation?

A

The volume of air exhnace between the atmospher and the alveoli per minute

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3
Q

Why is alveolar ventilation less than pulmonary ventilation

A

Due to the presence of anatomical dead space

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4
Q

What is the volume of anatomical dead space?

A

150ml

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5
Q

What is meant be the term ‘dead space’

A

the gas is not available for gas exchange

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6
Q

Which area of the lung is generally better ventilated?

A

The bottom (slight)

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7
Q

What area of the lung is generally better perfused?

A

Bottom

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8
Q

What is alveolar dead space?

A

Alveoli which are well ventilated but poorly perfused

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9
Q

What is the physiological dead space?

A

Alveolar dead space + anatomical dead space

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10
Q

What can increase alveolar dead space?

A

Disease

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11
Q

What happens if there is an accumulation of CO2 in the alveoli?

A

This indicates increased perfusion.

This results in a decrease in airway resistance and thus an increase in airflow.

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12
Q

What hapens if there is an increase in alveolar O2/

A

this indicated that this area of the lung is well ventilated

Vasodilation will now occur to direct blood flow to the well ventilated area

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13
Q

What happens if there is a decreased CO2 in the alveoli

A

this indicated poorly perfused lung tissue

Airway resistance will thus increase to limit airflow to that area

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14
Q

What happens if there is an decrease on oxygen

A

this indicates poor ventilation

Vasocontriction will occur to direct blood away from this area

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15
Q

What four factors influence the rate of gas exchange?

A

Partial pressure gradient
Diffusion Coefficient
Surface Area
Thickness of the alveolar membrane

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16
Q

What is Daltons law of partial pressures?

A

Total pressure exerted by a gaseous mixture= sum of the partial pressures of each of the individula components

17
Q

What is the partial pressure of a gas?

A

The pressure that one gas in a mixture would exert if it were the only gas present in the whole volume occupied by the mixture

18
Q

What is the alveolar gas equation

A

PAO2= PiO2- [PaCO2/0.8]

19
Q

What is atmospheric pressure?

A

760

20
Q

What is the water pressure in the lungs

A

47

21
Q

What is the pressure of inspired air

A

713

22
Q

What is the partial pressure of inspired oxygen

A

150

23
Q

What is the partial pressure of carbon dioxide in the capillaries

A

40

24
Q

What is the partial pressure of oxygen in alveolar air

A

100

25
Q

What offsets the fact that the partial pressure gradient for oxygen is so much higher than that of carbon dioxide

A

the diffusion coeeficient for carbon dioxide is twenty times that of oxygen

26
Q

What is the diffusion coefficient

A

the solubility of gas in membranes

27
Q

What would a big gradient between PAO2 and PaO2 indicate

A

Problems with gas exchange or a left to right shunt in the heart

28
Q

What is ficks law of diffusion

A

the amount of gas that moves across a sheet of tissue in a unit time is proportional to the area of the sheet but inversely proportional to its thickness