GI: Gastric Motility Flashcards

1
Q

What are the cells in the pyloric gland area?

A

D cells

G celss

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2
Q

What are the cells in the oxytic mucosa?

A

Chief
Enterochromaffin
Parietal

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3
Q

What do D cells secrete?

A

somatostatin

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4
Q

What do G cells secrete?

A

gastrin

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5
Q

What do chief cells secretes?

A

pepsinogen

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6
Q

What do enterocromaffin like cells secrete?

A

histamine

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7
Q

What do parietal cells secrete?

A

intrinsic factor

HCl

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8
Q

What does HCl do?

A

Activates pesinogen to pepsin
Denature proten
Kills bacteria

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9
Q

What does intrinsic factor do?

A

Binds vitamen B12 so that it can be absorbed in the intestine

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10
Q

What does histamine doe?

A

Stimulates HCl secretion

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11
Q

What does gastrin do?

A

Stimulates secretion of HCL

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12
Q

What does somatostatin do?

A

Inhibits secretion of Hcl

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13
Q

Where is HCl secreted into?

A

Canaliculus

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14
Q

What increases the activity f the proton pump?

A

Gastrin
Histamine
Parasympathetic activity

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15
Q

What muscarinic receptors work on parietal cells?

A

M3

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16
Q

What happens to the cannaliculur membrane when the parietal cell is in the activated state?

A

Becomes microvillus

17
Q

What are the three phases of gastric secretion?

A

Cephalic
Gastric
Intestinal

18
Q

What drives the secretion of somatostatin?

A

Low stomach lumen pH as occurs between meals