Respiratory - Embryology Flashcards
What are the lungs a derivative of?
Derivative of the foregut. Outpouching of oesophagus.
This forms a respiratory diverticulum with lung buds.
5th week —> Lungs buds enlarge to form left and right main bronchi.
List the stages of respiratory development
Embryonic, pseudoglandular, cannalicular, alveolar
What is produced during the alveolar stage?
Alveolar sacs, T1 and T2 pneumocytes.
When is surfactant produced?
From 34 weeks, with a dramatic increase pre-birth
Why so premature babies have low levels of surfactant?
Because they miss the dramatic increase pre-birth/the beginning of surfactant production at 34 weeks.
How are premature babies treated for low surfactant levels?
Given replacement surfactant.