Respiratory Dynamics: Resistance to Airflow (PK3) Flashcards
What is airflow resistance defined as?
Pressure difference required for a given flow
Normal airflow resistance
0.2kPa.L.s-1
What is the most frequent cause of ventilatory impairment?
Increased resistance to breathing
What is the difference between the start and end distending pressure on a static graph representing?
Work required to stretch the lungs (or compliance)
What is the difference between the start and end distending pressure on a dynamic graph representing?
Work required to stretch the lungs AND work required to move the air itself (dynamic resistance)
What percentage of dynamic resistance is friction in the airways?
80-90%
What percentage of dynamic resistance is lung tissue friction?
10-20%
Equation linking flow, change in pressure and resistance
Flow = ΔPressure / Resistance
Poiseuille’s equation
Flow = ΔPressure x (π x radius4) / (8 x length x viscosity)
What is resistance proportional to?
1 / Radius4
Where is most airway resistance found?
Upper airways (larynx/pharynx + large airways)