Alveolar-Arterial (A-a) PO2 Difference (PK5) Flashcards

1
Q

What is the value of PAO2?

A

13kPa

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2
Q

What is PaO2 where gas is exchanging?

A

13kPa

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3
Q

What is PaO2 when blood actually leaves the heart?

A

12kPa

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4
Q

2 reasons for drop in PaO2 by the time blood has left the heart

A
  • Shunts
  • Ventilation-perfusion mismatch
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5
Q

What causes the V/Q mismatch?

A
  • Lung receives 4 litres/min alveolar ventilation
  • Lung receives 5 litres/min blood flow
  • Therefore total lung V/Q ratio = 0.8
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6
Q

What increases the A-a difference?

A
  • Increasing shunt fraction
  • Increasing V/Q mismatch
  • Age (due to V/Q ratio change)
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