CO2 Dissociation Curve (PK7)

Question 1

Values showing the Haldane effect

Answer 1

• Arterial blood:
  > HbO2 = 97.5%
  > PCO2 = 5kPa
  > CO2 content = 480ml/L
• Venous blood:
  > HbO2 = 70%
  > PCO2 = 6kPa
  > CO2 content = 520ml/L

Question 2

2 factors accounting for Haldane effect

Answer 2

• Deoxy Hb 3.5x more effective at binding CO2
• Deoxy Hb binds H+ more avidly than HbO2

Question 3

What effect does the Haldane effect have on equilibrium, and what is the result?

Answer 3

• Pushes to the right
• More CO2 carried
• More O2 released