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PHARMACOLOGY > Respiratory Drugs - CLASSES/MECHANISMS > Flashcards

Respiratory Drugs - CLASSES/MECHANISMS Flashcards

1
Q

Formoterol

A

Long-acting beta-2 agonist

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2
Q

Diphenhydramine

A

1st generation antihistamine: Reversible inhibitor of H1 histamine receptors

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3
Q

Dimenhydrinate

A

1st generation antihistamine: Reversible inhibitor of H1 histamine receptors

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4
Q

Albuterol

A

Short-acting beta-2 agonist

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5
Q

Tadalafil

A

Inhibits PDE-5 - increases cGMP - prolonged vasodilatory effect of NO

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6
Q

Tiotropium

A

Muscarinic antagonist

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7
Q

Pseudoephedrine

A

Alpha-adrenergic agonists: Nasal decongestant

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8
Q

Dextromethorphan

A

Antitussive: Antagonizes NMDA glutamate receptors (synthetic codeine analog)

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9
Q

Chlorpheniramine

A

1st generation antihistamine: Reversible inhibitor of H1 histamine receptors

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10
Q

Zileuton

A

5-lipoxygenase pathway inhibitor

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11
Q

Bitolterol

A

Short-acting beta-2 agonist

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12
Q

Salmeterol

A

Long-acting beta-2 agonist

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13
Q

Ambrisentan

A

Competitive antagonist of endothelin-1 receptors - decreases pulmonary vascular resistance

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14
Q

N-acetylcysteine

A

Mucolytic - liqufies mucus in chronic bronchopulmonary diseases (e.g., COPD, CF) by disrupting disulfide bonds

Antidote for acetaminophen OD

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15
Q

Sildenafil

A

Inhibits PDE-5 - increases cGMP - prolonged vasodilatory effect of NO

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16
Q

Promethazine

A

1st generation antihistamine: Reversible inhibitor of H1 histamine receptors

17
Q

Pirbuterol

A

Short-acting beta-2 agonist

18
Q

Methacholine

A

Nonselective muscarinic receptor (M3) agonist

19
Q

Zafirlukast

A

Leukotriene receptor (CysLT1) inhibitor

20
Q

Epoprostenol

A

PGI2 (prostacyclin) with direct vasodilatory effects on pulmonary and systemic arterial vascular beds

Inhibit platelet aggregation

21
Q

Ipratropium

A

Muscarinic antagonist

22
Q

Bosentan

A

Competitive antagonist of endothelin-1 receptors - decreases pulmonary vascular resistance

23
Q

Phenylephrine

A

Alpha-adrenergic agonists: Nasal decongestant

24
Q

Fluticasone

A

Inhaled corticosteroid

25
Q

Loratadine

A

2nd generation antihistamine: Reversible inhibitor of H1 histamine receptors

26
Q

Treprostinil

A

PGI2 (prostacyclin) with direct vasodilatory effects on pulmonary and systemic arterial vascular beds

Inhibit platelet aggregation

27
Q

Omalizumab

A

Anti-IgE monoclonal antibody

28
Q

Theophylline

A

Phosphodiesterase inhibitor - increases cAMP - bronchodilation

29
Q

Iloprost

A

PGI2 (prostacyclin) with direct vasodilatory effects on pulmonary and systemic arterial vascular beds

Inhibit platelet aggregation

30
Q

Desloratadine

A

2nd generation antihistamine: Reversible inhibitor of H1 histamine receptors

31
Q

Hydroxyzine

A

1st generation antihistamine: Reversible inhibitor of H1 histamine receptors

32
Q

Fexofenadine

A

2nd generation antihistamine: Reversible inhibitor of H1 histamine receptors

33
Q

Guaifenesin

A

Expectorant - thins respiratory secretions; does not suppress cough

34
Q

Montelukast

A

Leukotriene receptor (CysLT1) inhibitor

35
Q

Budesonide

A

Inhaled corticosteroid

36
Q

Cetirizine

A

2nd generation antihistamine: Reversible inhibitor of H1 histamine receptors

PHARMACOLOGY (33 decks)

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