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pharmacology > Drug Reactions > Flashcards

Drug Reactions Flashcards

1
Q

Coronary vasospasm

A

Amphetamines
Cocaine
Ergot alkaloids
Sumatriptan

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2
Q

SLE-like syndrome

A 
Sulfa drugs
Hydralazine
Isoniazid
Procainamide
Phenytoin
Etanercept
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3
Q

Torsades

A 
Antiarrhythmics - class Ia, III
Antibiotics (macrolides)
Antipsychotics (haloperidol)
Antidepressants (TCAs)
Antiemetics (ondansetron)
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4
Q

Hypothyroidism

A

Lithium
Amiodarone
Sulfonamides

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5
Q

Drug reaction with eosinophilia and systemic symptoms (DRESS)

A

Allopurinol
Anticonvulsants (phenytoin, fosphenytoin)
Antibiotics
Sulfa drugs

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6
Q

Aplastic anemia

A 
Carbamazepine
Methimazole
Propylthiouracil (PTU)
NSAIDs
Benzene
Chloramphenicol
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7
Q

Thrombocytopenia

A

Heparin

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8
Q

Cinchonism (tinnitus, hearing/vision loss, psychosis, cognitive impairment)

A

Quinidine

Quinine

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9
Q

Andrenocortical insufficiency

A

HPA suppression secondary to glucocorticoid withdrawal

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10
Q

Osteoporosis

A 
Corticosteroids
Depot medroxyprogesterone acetate
GnRH agonists
Aromatase inhibitors
Anticonvulsants 
Heparin
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11
Q

Hot flashes

A

Tamoxifen

Clomiphene

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12
Q

Hemolysis in G6PD deficiency

A 
Isoniazid
Sulfonamides
Dapsone
Primaquine
Aspirin
Ibuprofen
Nitrofurantoin
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13
Q

Pancreatitis

A 
Didanosine
Corticosteroids
Alcohol
Valproate
Azathioprine
Diuretics (Furosemide, HCTZ)
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14
Q

Dilated cardiomyopathy

A

Doxorubicin, Daunorubicin

prevented with dextazoxane

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15
Q

Agranulocytosis

A 
Clozapine
Carbamazepine
Propylthiouracil (PTU)
Methimazole
Colchicine
Ganciclovir
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16
Q

Megaloblastic anemia

A

Hydroxyurea
Phenytoin
Methotrexate
Sulfa drugs

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17
Q

Parkinson-like syndrome

A

Antipsychotics
Reserpine
Metoclopramide

18
Q

Thrombotic complications

A

Combined oral contraceptives
Hormone replacement therapy
SERMs (tamoxifen, raloxifen, clomiphene)

19
Q

Focal to massive hepatic necrosis

A

Halothane
Amanita phalloides (death cap mushroom)
Valproate
Acetaminophen

20
Q

Direct Coombs-positive hemolytic anemia

A

Methyldopa

Penicillin

21
Q

Myopathy

A 
Statins
Fibrates
Niacin
Colchicine
Daptomycin
Hydroxychloroquine
Interferon-alpha
Penicillamine
Glucocorticoids
22
Q

Cutaneous flushing

A 
Vancomycin
Adenosine
Niacin
Nitrates
CCBs
Echinocandins (Anidulafungin, Caspofungin, Micafungin)
23
Q

Seizures

A 
Isoniazid (B6 deficiency)
Bupropion
Imipenem + Cilastatin
Tramadol
Enflurane
24
Q

Acute cholestatic hepatitis, jaundice

A

Erythromycin

25
Q

Photosensitivity

A

Sulfonamides
Amiodarone
Tetracyclines
5-FU

26
Q

Tardive dyskinesia

A

Antipsychotics

Metoclopramide

27
Q

Hepatitis

A 
Rifampin
Isoniazid 
Pyrazinamide
Statins
Fibrates
28
Q

Hyperglycemia

A 
Tacrolimus
Protease inhibitors
Niacin
HCTZ
Corticosteroids
29
Q

Fat redistribution

A

Protease inhibitors

Glucocorticoids

30
Q

Pseudomembranous colitis (C. difficile)

A

Ampicillin
Cephalosporins
Clindamycin
Fluoroquinolones

31
Q

Tendonitis, tendon rupture, and cartilage damage

A

Fluoroquinolones

32
Q

Pill-induced esophagitis

A 
Bisphosphonates
Ferrous sulfate
NSAIDs
KCl
Tetracyclines
33
Q

Diarrhea

A 
Acamprosate
Acarbose
Cholinesterase inhibitors
Colchicine
Erythromycin
Ezetimibe
Metformin
Misoprostol
Orlistat
Pramlintide
Quinidine
SSRIs
34
Q

Hyperuricemia (gout)

A 
Pyrazinamide
Thiazides
Furosemide
Niacin
Cyclosporine
35
Q

Gingival hyperplasia

A

Phenytoin
CCBs
Cyclosporine

36
Q

Stevens-Johnson syndrome

A

Anti-epileptic drugs (especially lamotrigine)
Allopurinol
Sulfa drugs
Penicillin

37
Q

Gray baby syndrome

A

Chloramphenicol

38
Q

Diabetes insipidus

A

Lithium

Demeclocycline

39
Q

SIADH

A

Carbamazepine
Cyclophosphamide
SSRIs

40
Q

Teeth discoloration

A

Tetracyclines

pharmacology (33 decks)

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