Psychiatry Drugs - CLASSES/MECHANISMS Flashcards
Iloperidone
Atypical antipsychotic
Desvenlafaxine
SNRI
Mechanism: Typical antipsychotics
Block D2 receptors (increasing cAMP)
Lurasidone
Atypical antipsychotic
Varenicline
Atypical antidepressant
Trazodone
Atypical antidepressant
Olanzapine
Atypical antipsychotic
Trifluoperazine
Typical antipsychotic
Haloperidol
Typical antipsychotic
Brexpiprazole
Atypical antipsychotic
Amitriptyline
TCA
Doxepin
TCA
Amoxapine
TCA
Bupropion
Atypical antidepressant
Nortriptyline
TCA
Tranylcypromine
MAO inhibitor
Mirtazapine
Atypical antidepressant
Lamotrigine (anticonsulvant)
Mood stabilizer
Mechanism: TCAs
Inhibit NE and 5-HT reuptake
Pimozide
Typical antipsychotic
List the mood stabilizers [5]
Lithium Valproate (anticonsulvant) Carbamazepine (anticonsulvant) Lamotrigine (anticonsulvant) Atypical antipsychotics
Aripiprazole
Atypical antipsychotic
Paliperidone
Atypical antipsychotic
Escitalopram
SSRI
Mechanism: Vilazodone
Inhibits 5-HT reuptake
5-HT1a partial agonist
Desipramine
TCA
Carbamazepine (anticonsulvant)
Mood stabilizer
Mechanism: Mirtazapine
Alpha-2 antagonist (increases release of NE and 5-HT)
Potent 5-HT2 and 5-HT3 receptor antagonist
H1 antagonist
Fluphenazine
Typical antipsychotic
Methylphenidate
CNS stimulant
Thioridazine
Typical antipsychotic - low potency
Phenelzine
MAO inhibitor
Venlafaxine
SNRI
Vortioxetine
Atypical antidepressant
Mechanism: CNS stimulants
Increase catecholamines in the synaptic cleft, especially NA and DA
Ziprasidone
Atypical antipsychotic
Clozapine
Atypical antipsychotic
Isocarboxazid
MAO inhibitor
Fluoxetine
SSRI
Sertraline
SSRI
Mechanism: Bupropion
Inhibits reuptake of NE and DA
Valproate (anticonsulvant)
Mood stabilizer
Thiothixene
Typical antipsychotic
Loxapine
Typical antipsychotic
Methamphetamine
CNS stimulant
Clomipramine
TCA
Mechanism: Vortioxetine
Inhibits 5-HT reuptake
5-HT1a agonist
5-HT3 antagonist
Citalopram
SSRI
Levomilnacipran
SNRI
Duloxetine
SNRI
Mechanism: Lithium
Not established
Possibly related to inhibition of phosphoinositol cascade
Vilazodone
Atypical antidepressant
Mechanism: SNRIs
Inhibit 5-HT and NE reuptake
Fluvoxamine
SSRI
Milnacipran
SNRI
Risperidone
Atypical antipsychotic
Selegiline
(Selective) MAO-B inhibitor
Mechanism: Atypical antipsychotics
Most are D2 antagonists
(Aripiprazole is a D2 partial agonist)
Varied effects on: 5-HT2 DA Alpha H1
Asenapine
Atypical antipsychotic
Mechanism: Verenicline
Nicotinic ACh receptor partial agonist
Buspirone
Stimulates 5-HT1a receptors
2nd line GAD
Mechanism: Trazodone
Primarily blocks: 5-HT2 Alpha-1 H1 Weakly inhibits 5-HT reuptake
Chlorpromazine
Typical antipsychotic - low potency
Dextroamphetamine
CNS stimulant
Mechanism: SSRIs
Inhibit 5-HT reuptake
Paroxetine
SSRI
Lithium
Mood stabilizer
Perphenazine
Typical antipsychotic
Quetiapine
Atypical antipsychotic
Mechanism: MAO inhibitors
Nonselective MAO inhibition - increases levels of amine NTs (NE, 5-HT, DA)
Selegiline is selective MAO-B inhibitor
Imipramine
TCA