Psychiatry Drugs - CLASSES/MECHANISMS Flashcards
1
Q
Iloperidone
A
Atypical antipsychotic
2
Q
Desvenlafaxine
A
SNRI
3
Q
Mechanism: Typical antipsychotics
A
Block D2 receptors (increasing cAMP)
4
Q
Lurasidone
A
Atypical antipsychotic
5
Q
Varenicline
A
Atypical antidepressant
6
Q
Trazodone
A
Atypical antidepressant
7
Q
Olanzapine
A
Atypical antipsychotic
8
Q
Trifluoperazine
A
Typical antipsychotic
9
Q
Haloperidol
A
Typical antipsychotic
10
Q
Brexpiprazole
A
Atypical antipsychotic
11
Q
Amitriptyline
A
TCA
12
Q
Doxepin
A
TCA
13
Q
Amoxapine
A
TCA
14
Q
Bupropion
A
Atypical antidepressant
15
Q
Nortriptyline
A
TCA
16
Q
Tranylcypromine
A
MAO inhibitor
17
Q
Mirtazapine
A
Atypical antidepressant
18
Q
Lamotrigine (anticonsulvant)
A
Mood stabilizer
19
Q
Mechanism: TCAs
A
Inhibit NE and 5-HT reuptake
20
Q
Pimozide
A
Typical antipsychotic
21
Q
List the mood stabilizers [5]
A
Lithium Valproate (anticonsulvant) Carbamazepine (anticonsulvant) Lamotrigine (anticonsulvant) Atypical antipsychotics
22
Q
Aripiprazole
A
Atypical antipsychotic
23
Q
Paliperidone
A
Atypical antipsychotic
24
Q
Escitalopram
A
SSRI
25
Mechanism: Vilazodone
Inhibits 5-HT reuptake
| 5-HT1a partial agonist
26
Desipramine
TCA
27
Carbamazepine (anticonsulvant)
Mood stabilizer
28
Mechanism: Mirtazapine
Alpha-2 antagonist (increases release of NE and 5-HT)
Potent 5-HT2 and 5-HT3 receptor antagonist
H1 antagonist
29
Fluphenazine
Typical antipsychotic
30
Methylphenidate
CNS stimulant
31
Thioridazine
Typical antipsychotic - low potency
32
Phenelzine
MAO inhibitor
33
Venlafaxine
SNRI
34
Vortioxetine
Atypical antidepressant
35
Mechanism: CNS stimulants
Increase catecholamines in the synaptic cleft, especially NA and DA
36
Ziprasidone
Atypical antipsychotic
37
Clozapine
Atypical antipsychotic
38
Isocarboxazid
MAO inhibitor
39
Fluoxetine
SSRI
40
Sertraline
SSRI
41
Mechanism: Bupropion
Inhibits reuptake of NE and DA
42
Valproate (anticonsulvant)
Mood stabilizer
43
Thiothixene
Typical antipsychotic
44
Loxapine
Typical antipsychotic
45
Methamphetamine
CNS stimulant
46
Clomipramine
TCA
47
Mechanism: Vortioxetine
Inhibits 5-HT reuptake
5-HT1a agonist
5-HT3 antagonist
48
Citalopram
SSRI
49
Levomilnacipran
SNRI
50
Duloxetine
SNRI
51
Mechanism: Lithium
Not established
| Possibly related to inhibition of phosphoinositol cascade
52
Vilazodone
Atypical antidepressant
53
Mechanism: SNRIs
Inhibit 5-HT and NE reuptake
54
Fluvoxamine
SSRI
55
Milnacipran
SNRI
56
Risperidone
Atypical antipsychotic
57
Selegiline
(Selective) MAO-B inhibitor
58
Mechanism: Atypical antipsychotics
Most are D2 antagonists
(Aripiprazole is a D2 partial agonist)
```
Varied effects on:
5-HT2
DA
Alpha
H1
```
59
Asenapine
Atypical antipsychotic
60
Mechanism: Verenicline
Nicotinic ACh receptor partial agonist
61
Buspirone
Stimulates 5-HT1a receptors
| 2nd line GAD
62
Mechanism: Trazodone
```
Primarily blocks:
5-HT2
Alpha-1
H1
Weakly inhibits 5-HT reuptake
```
63
Chlorpromazine
Typical antipsychotic - low potency
64
Dextroamphetamine
CNS stimulant
65
Mechanism: SSRIs
Inhibit 5-HT reuptake
66
Paroxetine
SSRI
67
Lithium
Mood stabilizer
68
Perphenazine
Typical antipsychotic
69
Quetiapine
Atypical antipsychotic
70
Mechanism: MAO inhibitors
Nonselective MAO inhibition - increases levels of amine NTs (NE, 5-HT, DA)
Selegiline is selective MAO-B inhibitor
71
Imipramine
TCA
