Psychiatry Drugs - CLASSES/MECHANISMS Flashcards

1
Q

Iloperidone

A

Atypical antipsychotic

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2
Q

Desvenlafaxine

A

SNRI

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3
Q

Mechanism: Typical antipsychotics

A

Block D2 receptors (increasing cAMP)

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4
Q

Lurasidone

A

Atypical antipsychotic

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5
Q

Varenicline

A

Atypical antidepressant

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6
Q

Trazodone

A

Atypical antidepressant

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7
Q

Olanzapine

A

Atypical antipsychotic

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8
Q

Trifluoperazine

A

Typical antipsychotic

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9
Q

Haloperidol

A

Typical antipsychotic

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10
Q

Brexpiprazole

A

Atypical antipsychotic

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11
Q

Amitriptyline

A

TCA

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12
Q

Doxepin

A

TCA

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13
Q

Amoxapine

A

TCA

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14
Q

Bupropion

A

Atypical antidepressant

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15
Q

Nortriptyline

A

TCA

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16
Q

Tranylcypromine

A

MAO inhibitor

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17
Q

Mirtazapine

A

Atypical antidepressant

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18
Q

Lamotrigine (anticonsulvant)

A

Mood stabilizer

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19
Q

Mechanism: TCAs

A

Inhibit NE and 5-HT reuptake

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20
Q

Pimozide

A

Typical antipsychotic

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21
Q

List the mood stabilizers [5]

A
Lithium
Valproate (anticonsulvant)
Carbamazepine (anticonsulvant)
Lamotrigine (anticonsulvant)
Atypical antipsychotics
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22
Q

Aripiprazole

A

Atypical antipsychotic

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23
Q

Paliperidone

A

Atypical antipsychotic

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24
Q

Escitalopram

A

SSRI

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25
Q

Mechanism: Vilazodone

A

Inhibits 5-HT reuptake

5-HT1a partial agonist

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26
Q

Desipramine

A

TCA

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27
Q

Carbamazepine (anticonsulvant)

A

Mood stabilizer

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28
Q

Mechanism: Mirtazapine

A

Alpha-2 antagonist (increases release of NE and 5-HT)
Potent 5-HT2 and 5-HT3 receptor antagonist
H1 antagonist

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29
Q

Fluphenazine

A

Typical antipsychotic

30
Q

Methylphenidate

A

CNS stimulant

31
Q

Thioridazine

A

Typical antipsychotic - low potency

32
Q

Phenelzine

A

MAO inhibitor

33
Q

Venlafaxine

A

SNRI

34
Q

Vortioxetine

A

Atypical antidepressant

35
Q

Mechanism: CNS stimulants

A

Increase catecholamines in the synaptic cleft, especially NA and DA

36
Q

Ziprasidone

A

Atypical antipsychotic

37
Q

Clozapine

A

Atypical antipsychotic

38
Q

Isocarboxazid

A

MAO inhibitor

39
Q

Fluoxetine

A

SSRI

40
Q

Sertraline

A

SSRI

41
Q

Mechanism: Bupropion

A

Inhibits reuptake of NE and DA

42
Q

Valproate (anticonsulvant)

A

Mood stabilizer

43
Q

Thiothixene

A

Typical antipsychotic

44
Q

Loxapine

A

Typical antipsychotic

45
Q

Methamphetamine

A

CNS stimulant

46
Q

Clomipramine

A

TCA

47
Q

Mechanism: Vortioxetine

A

Inhibits 5-HT reuptake
5-HT1a agonist
5-HT3 antagonist

48
Q

Citalopram

A

SSRI

49
Q

Levomilnacipran

A

SNRI

50
Q

Duloxetine

A

SNRI

51
Q

Mechanism: Lithium

A

Not established

Possibly related to inhibition of phosphoinositol cascade

52
Q

Vilazodone

A

Atypical antidepressant

53
Q

Mechanism: SNRIs

A

Inhibit 5-HT and NE reuptake

54
Q

Fluvoxamine

A

SSRI

55
Q

Milnacipran

A

SNRI

56
Q

Risperidone

A

Atypical antipsychotic

57
Q

Selegiline

A

(Selective) MAO-B inhibitor

58
Q

Mechanism: Atypical antipsychotics

A

Most are D2 antagonists
(Aripiprazole is a D2 partial agonist)

Varied effects on:
5-HT2
DA
Alpha
H1
59
Q

Asenapine

A

Atypical antipsychotic

60
Q

Mechanism: Verenicline

A

Nicotinic ACh receptor partial agonist

61
Q

Buspirone

A

Stimulates 5-HT1a receptors

2nd line GAD

62
Q

Mechanism: Trazodone

A
Primarily blocks: 
5-HT2
Alpha-1
H1 
Weakly inhibits 5-HT reuptake
63
Q

Chlorpromazine

A

Typical antipsychotic - low potency

64
Q

Dextroamphetamine

A

CNS stimulant

65
Q

Mechanism: SSRIs

A

Inhibit 5-HT reuptake

66
Q

Paroxetine

A

SSRI

67
Q

Lithium

A

Mood stabilizer

68
Q

Perphenazine

A

Typical antipsychotic

69
Q

Quetiapine

A

Atypical antipsychotic

70
Q

Mechanism: MAO inhibitors

A

Nonselective MAO inhibition - increases levels of amine NTs (NE, 5-HT, DA)

Selegiline is selective MAO-B inhibitor

71
Q

Imipramine

A

TCA