respiratory drugs: bronchodilators Flashcards
Bronchoconstriction/bronchodilators usually affect (part of resp tract)
terminal bronchules – smallest of the tree
bronchoconstriction can be caused by (SNS/PNS) stimulation
PNS
Bronchoconstriction is caused by constriction of smooth muscle around (part of resp tract)
bronchioles
2 most common causes of bronchoconstriction
- histamine release (allergies leading to it)
- toxicity
histamine receptors cause (contraction/relaxation)
contraction
Beta-2 receptors cause (contraction/relaxation)
relaxation
- SNS
bronchodilators are available as (3)
- inhalant
- oral
- injectable
formulations
these cause bronchodilation by interfering with smooth muscle cell metabolism (relax)
Methylxanthines
these may cause CNS stimulation and GI upset
Methylxanthines
these have narrow therapeutic range
Methylxanthines
these are metabolized in the liver by enzymes that metabolize many other veterinary drugs
Methylxanthines