Hematologic emergencies: primary hemostasis abnormalities

Question 1

3 primary hemostasis abnormalities

Answer 1

• thrombocytopenia
• thrombopathia
• von Willebrand’s Factor (vWF) deficiency

Question 2

thrombocytopenia can be caused by 3 things

Answer 2

• decreased platelet production – tickborne infection
• increased platelet consumption
• increase platelet destruction
  Immune-mediated thrombocytopenia (IMT)

Question 3

what 3 things, other than the unknown, can cause immune-mediated thrombocytopenia?

Answer 3

• vaccines
• cancer
• drugs

Question 4

this is Abnormal platelet function – don’t work normally like they should

Answer 4

Thrombopathia

Question 5

what can affect platelet function?

Answer 5

NSAIDs - i.e. Rimadyl

Question 6

thombopathia can be (2)

Answer 6

inherited or acquired

Question 7

this is the most common hereditary bleeding defect in dogs

Answer 7

von Willebrand’s Factor (vWF) deficiency

Question 8

what is von Willebrand’s Factor (vWF)?

Answer 8

chemical substance that adheres to exposed tissue – sticky surface at which platelets will adhere to

Question 9

which 4 breeds are most commonly known for having vWF?

Answer 9

• dobermans
• german shepherds
• golden retrievers
• rotties

Question 10

can you measure vWF in blood?

Answer 10

yes

Question 11

mucosal surface bleeding and hemorrhage is often seen after surgery or trauma because of this

Answer 11

von Willebrand’s Factor (vWF) deficiency

Question 12

Administer ____ high in vWF concentrations (pre/post)operatively

Answer 12

cryoprecipitate

- PREoperatively