Respiratory Burst Flashcards by Farida Adams

Q

Enzyme complex that initiates respiratory burst in phagocytes

A

NADPH oxidase

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Q

Deficiency of NADPH oxidase causes this disease

A

Chronic granulomatous disease

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Q

Enzyme that converts superoxide to hydrogen peroxide

A

Superoxide dismutase

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Q

Enzyme that uses H2O2 to generate hypochlorous acid (bleach)

A

Myeloperoxidase

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Q

Blue-green pigment in pus is due to this enzyme

A

Myeloperoxidase

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Q

Bacterial enzyme that neutralizes H2O2, reducing ROS killing ability

A

Catalase

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Q

Enzyme from the HMP shunt that regenerates NADPH

A

Glucose-6-phosphate dehydrogenase (G6PD)

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