Immunosuppressants Flashcards
1
Q
Immunosuppressant that binds cyclophilin and inhibits calcineurin
A
Cyclosporine
2
Q
Immunosuppressant that binds FKBP and inhibits calcineurin
A
Tacrolimus (FK506)
3
Q
Immunosuppressant that inhibits mTOR and blocks IL-2 response
A
Sirolimus (Rapamycin)
4
Q
Monoclonal antibody that blocks IL-2R
A
Basiliximab
5
Q
Purine synthesis inhibitor used in autoimmune conditions
A
Azathioprine
6
Q
Drug that inhibits IMP dehydrogenase in B and T cells
A
Mycophenolate mofetil
7
Q
Immunosuppressant that inhibits NF-κB and reduces cytokine transcription
A
Glucocorticoids
