Interferons Flashcards
1
Q
Three main types of interferons
A
IFN-α, IFN-β, IFN-γ
2
Q
Mechanism of action of interferons in viral defense
A
Downregulate protein synthesis and upregulate MHC expression
3
Q
Role of interferons in the immune response
A
Activate antiviral defense and antitumor immunity
4
Q
Chronic diseases treated with interferons
A
Chronic HBV, HCV, Kaposi sarcoma, RCC, malignant melanoma, MS
5
Q
Common adverse effects of interferons
A
Flulike symptoms, depression, neutropenia, myopathy, autoimmunity
