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Formulary > Respiratory > Flashcards

Respiratory Flashcards

1
Q

Tiotropium: Action

A

Antimuscarinic

M3 antagonist => reduce smooth muscle contraction and mucus production => bronchodilate

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2
Q

Tiotropium: Indications (2)

A

Asthma

COPD

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3
Q

Tiotropium: Side Effects (3)

A

Dry mouth
Throat irritation
Tachycardia

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4
Q

Prednisolone: Action

A

Corticosteroid

Transactivates gene expression => anti-inflammatory properties and increased gluconeogenesis

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5
Q

Prednisolone: Indications (3)

A

Allergic/inflammatory disorders
IBD
Asthma

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6
Q

Prednisolone: Side Effects (5)

A 
Immunosuppression
Osteoporosis
Muscle weakness
Skin thinning
Gastritis
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7
Q

Prednisolone: Interaction

A

Increased hypokalaemia with B2 agonist, theophylline and loop/thiazide diuretics

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8
Q

Theophylline: Action

A

Competitive phosphodiesterase inhibitor => reduce inflammation and innate immunity

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9
Q

Theophylline: Indication

A

Severe acute asthma

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10
Q

Theophylline: Contraindications (2)

A

Arrhythmia

Hypertension

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11
Q

Theophylline: Side Effects (3)

A

Palpitation
Tachycardia
Arrhythmia

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12
Q

Theophylline: Interaction

A

Plasma concentration increased by CCB, ciprofloxacin and erythromycin

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13
Q

Salbutamol: Action

A

B2 agonist

Activate B receptor => SM relaxation and airway dilation

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14
Q

Salbutamol: Indications (2)

A

Asthma

COPD

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15
Q

Salbutamol: Side Effects (2)

A

Fine tremor

Tension

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16
Q

Salbutamol: Interaction

A

Increased risk of hypokalaemia with corticosteroids and theophylline

Formulary (9 decks)

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