Psychiatry

Question 1

Amitryptilline: Action

Answer 1

Tricyclic antidepressant

Inhibit serotonin neuronal reuptake

Question 2

Amitryptilline: Indications (2)

Answer 2

Mild-mod depression (2nd line)

Neuropathic pain

Question 3

Amitryptilline: Side Effects (5)

Answer 3

Dry mouth
Constipation
Hypotension
Convulsions
Urinary retention

Question 4

Amitryptilline: Interaction

Answer 4

Hypertension/ serotonin syndrome increased with MAOis

Question 5

Citalopram: Action

Answer 5

SSRI

Inhibit serotonin reuptake

Question 6

Citalopram: Indications (3)

Answer 6

Moderate- severe depression
Panic disorder
OCD

Question 7

Citalopram: Contraindications

Answer 7

Manic phase

Question 8

Citalopram: Side Effects (3)

Answer 8

Appetite and weight changes
Suicidal thoughts
Prolong QT interval

Question 9

Citalopram: Interaction

Answer 9

Do no prescribe with w drugs prolonging QT interval

Question 10

Diazepam: Action

Answer 10

Benzodiazepine

Enhance GABA binding => widespread depressant effect

Question 11

Diazepam: Indications (3)

Answer 11

Seizures
Alcohol withdrawal
Short term relief of severe anxiety and insomnia

Question 12

Diazepam: Contraindication

Answer 12

Respiratory depression

Question 13

Donezepil: Action

Answer 13

Acetylcholinesterase inhibitor

Inhibit acetylcholine hydrolysis => increase concentration

Question 14

Donezepil: Indication

Answer 14

Mild to mod Alzheimer’s

Question 15

Donezepil: Side Effects (4)

Answer 15

Insomnia
Syncope
Hallucination
Muscle cramps