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Formulary > GI > Flashcards

GI Flashcards

1
Q

Omeprazole: Action

A

PPI

Inhibit H/K ATPase in parietal cells to decrease acid secretion

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2
Q

Omeprazole: Indications (4)

A

Peptic ulcers
Dyspepsia
GORD
H pylori

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3
Q

Omeprazole: Side Effects (2)

A

Headache

Hypomagnesaemia

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4
Q

Omeprazole: Interaction

A

Lowers effect of clopidogrel

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5
Q

Ranitidine: Action

A

H2 antagonist

Inhibits histamine at H2 receptor to decrease acid secretion

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6
Q

Ranitidine: Indications (3)

A

Gastric/duodenal ulcers
GORD
Dyspepsia

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7
Q

Loperamide: Action

A

Anti motility.

u opioid receptor agonist => increase time in bowel and increase water reabsorption

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8
Q

Loperamide: Contraindications (2)

A

UC

Antibiotic-associated colitis

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9
Q

Loperamide: Side Effects (2)

A

Flatulence

Abdo pain

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10
Q

Senna: Action

A

Stimulant laxative

Act on intestinal mucous/nerve plexus => alter ion and water secretion and stimulate peristalsis

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11
Q

Senna: Contraindication

A

Obstruction

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12
Q

Senna: Side Effect

A

Hypokalaemia

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13
Q

Mesalazine: Action

A

Aminosalicylate

Alter cytokine release

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14
Q

Mesalazine: Indications (3)

A

Colitis
Crohn’s
IBS

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15
Q

Mesalazine: Side Effects (5)

A 
Pancreatitis
Hepatitis
Lung disorders
Blood disorders
Peripheral neuropathy
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16
Q

Metoclopramide: Action

A

Anti-emetic

Dopamine d2 receptor antagonist

17
Q

Metoclopramide: Contraindications (3)

A

GI obstruction, perforation or haemorrhage

18
Q

Metoclopramide: Side Effects (3)

A

Extrapyramidal effects
Menstrual changes
Gynaecomastia

Formulary (9 decks)

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