Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Formulary > Endocrine drugs > Flashcards

Endocrine drugs Flashcards

1
Q

Fludrocortisone: Action

A

Binds to mineralocorticoid receptor => increase ion and water transport => increase fluid volume, bp and potassium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fludrocortisone: Indication

A

Adrenocortical insufficiency (Addison’s)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fludrocortisone: Side Effects (3)

A

Hypertension
Sodium/water retention
Potassium/calcium loss

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Insulin: Action

A

Stimulates uptake of blood glucose (drive potassium into cells).
Stimulate glycogen, lipid and protein synthesis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Insulin: Indications (3)

A

DM
Diabetic emergencies
Hyperkalaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Insulin: Side Effects (2)

A

Hypoglycaemia

Lipohypertrophy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Insulin: Interaction

A

Increased insulin requirements with corticosteroids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Gliclazide: Action

A

Sulphonylurea

Stimulate pancreatic insulin secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Gliclazide: Indication

A

DM T2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Gliclazide: Side Effects (2)

A

Hypoglycaemia

Hepatic toxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Gliclazide: Interaction

A

Decreased efficacy with prednisolone, thiazide and loop diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Metformin: Action

A

Biguanide

Increases insulin sensitivity. Suppress hepatic glucose production and intestinal absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Metformin: Indication

A

DM T2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Metformin: Contraindication (3)

A

Severe renal impairment
AKI
Tissue hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Metformin: Side Effects (2)

A

Weight loss

Lactic acidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Metformin: Interaction

A

Withhold 48 hrs before and after IV contrast

17
Q

Levothyroxine: Action

A

Replace T3 and T4

18
Q

Levothyroxine: Contraindication

A

Caution in coronary artery disease

19
Q

Levothyroxine: Side Effects (3)

A

Palpitations
Arrhythmias
Angina

20
Q

Levothyroxine: Interaction

A

Increase warfarin requirement and enhances

21
Q

Carbimazole: Action

A

Converted to methimazole => inhibit thyroid peroxidase => lower T3 and T4

22
Q

Carbimazole: Contraindication

A

Blood disorder

23
Q

Carbimazole: Side Effects (6)

A 
Taste disturbance
Fever
Rash
Arthralgia
Myopathy
Alopecia
24
Q

Carbimazole: Interaction

A

Enhance warfarin

25
Q

Alendronate: Action

A

Biphosphonate

Inhibit osteoclasts => reduce bone turnover

26
Q

Alendronate: Indications (4)

A

Osteoporosis
Severe hypercalcaemia
Paget’s disease
Prevent fracture in myeloma/breast cancer

27
Q

Alendronate: Contraindications (2)

A

Renal impairment

Hypocalcaemia

28
Q

Alendronate: Side Effects (2)

A

Oesophagitis

Hypophosphataemia

29
Q

Calcium and Vitamin D: Indications (4)

A

Osteoporosis
CKD
C= severe hyperkalaemia, hypocalcaemia

30
Q

Calcium and Vitamin D: Action (2)

A 
C= controls muscles, nerves and clotting
D= control calcium homeostasis
31
Q

Calcium and Vitamin D: Side Effects (2)

A

Dyspepsia

Constipation

32
Q

Calcium and Vitamin D: Interaction

A

Calcium decreases absorption of iron, biphosphonates, tetracyclines and levothyroxine

Formulary (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions