Respiratory Flashcards

1
Q

What are ecg findings in PE?

A

large S wave in lead I, a large Q wave in lead III and an inverted T wave in lead III

RBBB (as right heart strain)
RAD
Sinus tahcycardia

TWI (if RV ischaemia)

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2
Q

Management of high altitude cerebral oedema?

A

Descent + dexamethasone

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3
Q

Best way to monitor progression in COPD?

A

FEV1

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4
Q

Diagnosing asthma in patients <5 years?

A

Clinical judgement

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5
Q

Diagnosing asthma in patients 5-16 yo?

A

1) All patient Spirometry with bronchodilator reversibility (BDR) test
2) FeNO (fraction exhaled nitrous oxide) if normal spirometry or obstructive spirometry with negative BDR test

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6
Q

Diagnosing asthma in patients 17+?

A

1) ask all patients if symptoms better away from work - if so, refer for possible occupational asthma
2) All patients Spirometry with bronchodilator reversibility (BDR) test
3) All patients FeNO test

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7
Q

What makes a positive FeNO test?

A

Adults: >=40ppb

Children: >=35ppb

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8
Q

What spirometry result indicates obstructive disease?

A

FEV1/FVC <70%

FVC normal

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9
Q

What spirometry result indicates restrictive disease?

A

Both FEV1 + FVC reduced –> therefore FEV1/FVC normal

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10
Q

What is allergic bronchopulmonary aspergillosis?

A

Results from allergy to aspergillus spores

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11
Q

If a question states bronchiectasis with eosinophilia what is the likely diagnosis?

A

allergic bronchopulmonary aspergillosis

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12
Q

How does allergic bronchopulmonary aspergillosis present?

A

Bronchoconstriction [wheeze, cough, dyspnoea] (may have asthma diagnosis)

with PROXIMAL bronchiectasis

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13
Q

What is the treatment of allergic bronchopulmonary aspergillosis?

A

steroids

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14
Q

Where does absestos cause lung fibrosis?

A

lower zones

From the roof

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15
Q

What are the causes of upper zone fibrosis?

A
CHARTS
C - Coal worker's pneumoconiosis
H - Histiocytosis/ hypersensitivity pneumonitis
A - Ankylosing spondylitis
R - Radiation
T - Tuberculosis
S - Silicosis/sarcoidosis
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16
Q

What are the causes of lower zone fibrosis?

A

idiopathic pulmonary fibrosis

most connective tissue disorders (except ankylosing spondylitis) e.g. SLE

drug-induced: amiodarone, bleomycin, methotrexate

asbestosis

17
Q

What is the initial settings for BIPAP in COPD?

A

IPAP - 10cm H2O

EPAP - 5cm H2O

18
Q

what is brupropion contraindicated in?

A

Epilepsy, pregnancy + breast feeding

19
Q

What condition should you use varenicline with caution in?

A

Depression / self-harm history as increased risk of relapse

20
Q

What are the indications for corticosteroid treatment in sarcoidosis?

A
PUNCH:
Parenchymal lung disease
Uveitis
neurological or cardiac involvement
Hypercalcaemia
21
Q

commonest cause of infective exacerbation COPD?

A

Haemophilus influenzae

> strep pneumoniae > moraxella catarrhalis

22
Q

In exacerbations of COPD what do NICE recommend when to give antibiotics/treat as infective exacerbation?

A

if sputum purulent or clinical signs of pneumonia (including CXR showing consolidation; or inflam markers raised)

23
Q

What is Churg strauss syndrome? What is seen on serology

A

Eosinophilic granulomatosis with polyangitis

pANCA

24
Q

What is seen on serology with granulomatosis with polyangitis?

25
Give some presenting features of granulomatosis with polyangitis
URT sx's: epsitaxis, sinusitis, nasal crusting LRT: dsypnoea, haemoptysis Rapidly progressive Glomerulonephritis / AKI / renal failure Saddle shaped nose Vasculitic rash etc
26
If COPD not controlled with SABA or SAMA inhaler, what next?
Depends on whether asthmatic features/steroid responsive or not if asthamtuc features/steroid responsive: LABA + ICS If not: LABA + LAMA
27
First line copd treatment
SABA or same
28
What features may indicate if a pt with COPD would be steroid responsive?
Previous diagnosis asthma or atopy Raised eosinophil count Substantial variation in FEV1 over time Substantial diurnal variation in peak flow
29
Example of SAMA + LAMA
SAMA - ipratropium bromide LAMA - tiotropium bromide
30
What factors improve survival in stable COPD patients?
LTOT Smoking cessation Lung volume reduction surgery
31
In patients who are young with emphysema what should you do / suspect?
A1AT levels ?deficiency
32
What is the triangle of safety in chest drain insertion?
base of the axilla, lateral edge pectoralis major, 5th intercostal space and the anterior border of latissimus dorsi
33
Aminophylline MOA?
Phosphodiesterase inhibitor --> ^ cAMP --> to relax smooth muscle and to relieve bronchial spasm Also stabilise mast cell membrane
34
What types of lung cancer is associated with cavitating lesions?
Squamous cell
35
What is the investigation of choice for sleep apnoea?
Polysomnography
36
EXAM: What defines a large pneumothorax?
>2cm