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MRCP Part 1 > Dermatology > Flashcards

Dermatology Flashcards

1
Q

What are the 4 differentials of shin lesions

A

Erythema nodosum
Pretibial myxoedema
Pyoderma gangrenosum
Necrobiosis lipoidica diabeticorum

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2
Q

Give two skin reactions associated with inflammatory bowel disease

A

Pyoderma gangrenosum

Erythema nodosum

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3
Q

List some causes of erythema nodosum

A

streptococcal infections, sarcoidosis, IBD, drugs (penicillins, sulphonamides, OCP)

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4
Q

What antibodies are seen in pemphigus vulgaris?

A

Desmoglein antibodies

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5
Q

What is the treatment for rosacea?

A

Mild/mod: topical metronidazole

Severe: oral tetracycline

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6
Q

Give two conditions associated with seborrheic dermatitis

A

HIV

Parkinsons disease

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7
Q

Give two conditions associated with malassazia furfur

A

Seborrheic dermatitis

ptitiryasis versicolor

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8
Q

What malignancy is associated with acanthosis nigricans?

A

gastrointestinal adenocarcinoma / gastric cancer

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9
Q

What is pretibial myxoedema associated with?

A

Hyperthyroid (despite the name)

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10
Q

What does immunofluorescence show in bullous pemphigoid?

A

immunofluorescence shows IgG and C3 at the dermoepidermal junction

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11
Q

What antibodies are seen in bullous pemphigoig?

A

Hemidescmosomal BP antigens

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12
Q

Commonest cause of Erythema multiforme

A

HSV

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13
Q

How does systemic mastocytosis present? What do you look for in the urine + serum?

A

(Neoplastic proliferation of mast cells)

Presentation:
urticaria pigmentosa - produces a wheal on rubbing (Darier's sign)
flushing
abdominal pain
monocytosis on the blood film

Ix:
Urinary histamine
Raised serum triptase

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14
Q

Acitinic keratosis treatment

A

flurouracil

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15
Q

Treatment of keloid scars

A

intra-lesional steroids e.g. triamcinolone

Removal

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16
Q

What causes pallegra? Clinical features?

A

nicotinic acid (niacin) deficiency (e.g. in isoniazid therapy)

D's:
dermatitis (brown scaly rash on sun-exposed sites - termed Casal's necklace if around neck)
diarrhoea
dementia, depression
death if not treated
17
Q

What paraneoplastic skin condition is related to gastric cancer?

A

nigricans acanthosis

18
Q

What paraneoplastic skin condition is related to lymphoma?

A

Erythroderma

19
Q

What paraneoplastic skin condition is related to lung cancer?

A

Dermatomyositis

Erythema gyratum repens (wood grain appearance)

20
Q

First line hyperhydrosis

A

topical aluminium chloride

21
Q

What drugs exacerbate plaque psoriasis?

A

beta blockers, lithium, antimalarials (chloroquine and hydroxychloroquine), NSAIDs and ACE inhibitors, infliximab

22
Q

What might trigger guttate psoriasis?

A

Streptococcal infection

23
Q

Organism that causes erisepylas?

A

Group A strep

24
Q

Causes of tinea capitis

A

Trichophyton tonsuras or M. canis

Causes alopecia
Green-blue in fluorescent light

MRCP Part 1 (19 decks)

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