Psychiatry

Question 1

What drugs to avoid in Lithium?

Answer 1

THIAZIDE diuretics - reduce renal excretion of renal
(other diuretics)
NSAIDs
ACEi’s

Question 2

At doses higher then 225mg venlafaxine what do you need to monitor and why?

Answer 2

BP + ECG monitoring 6 monthly - risk of HTN + prolonged QTc

Question 3

What is a risk in MOA inhibitors?

Answer 3

If eat tyrosine rich foods –> hypertensive crisis

Question 4

Commonest side effect with olanzapine?

Answer 4

Weight gain

Question 5

What is the risk of atypical antipsychotics in the elderly?

Answer 5

In general: parkinsonism (witgh typical)

But with atypical: VTE + stroke

Question 6

What are some complications with clozapine?

Answer 6

agranulocytosis (1%), neutropaenia (3%)
reduced seizure threshold - can induce seizures in up to 3% of patients
constipation / Bowel obstruction
myocarditis: a baseline ECG should be taken before starting treatment
hypersalivation

Question 7

SSRI with highest risk of discontinuation syndrome?

Answer 7

Paroxetinec

Question 8

Cotard delusion

Answer 8

believe they are dead or dying

Question 9

De Clerambault’s syndrome

Answer 9

Delusion that someone famous is in love with them

Question 10

If CBT + EMDR ineffective in PTSD what to do next?

Answer 10

venlafaxine or a SSRI