RESP GX Flashcards

1
Q

partial pressure of nitrogen in the atmosphere is?

A

600 mmHg

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2
Q

partial pressure of oxygen in the atmosphere is?

A

160 mmHg

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3
Q

what are the four important partial pressures to consider?

A

PO2, PCO2, PH2O, and PN2

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4
Q

PH2O and PN2 are what in the atmosphere?

A

zero

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5
Q

what is the inhaled partial pressure of oxygen and nitrogen?

A

O2 is 150 mmHg

N2 is 563 mmHg

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6
Q

typical functional residual capacity?

A

2.3 L

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7
Q

how many ml of the 500 ml we inhale make it to the alveoli?

A

350 mL

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8
Q

each breath replace how much of the gas in the lungs?

A

15%, see below

350/2300

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9
Q

normal alveolar respiration at rest is how much? how much in mL of O2 and CO2 leave the blood?

A

4.2 L/min

250 mL of O2 enter blood and 200 mL of CO2 leave the blood

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10
Q

during exercise, alveolar ventilation rises to how much? (hint in L/min)

A

17 L/min

partial pressures of the gases stay the same no what the activity

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11
Q

T/F, CO2 has much higher solubility coefficient than oxygen?

A

T, more soluble than most gases

imp because this determines how much gas can be found in the plasma

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12
Q

what are the factors that affect diffusion besides partial pressure?

A

cross sectional
solubility coefficient
distance
molecular weight

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13
Q

what are the partial pressures of oxygen, CO2, nitrogen?

A
  1. 0
  2. 3
  3. 53
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14
Q

how many alveoli in the two lungs?

A

300 million

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15
Q

total area of diffusion across the rest units is how much in adults?

A

50-100 m^2

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16
Q

total amount of blood in the lungs?

A

60-140 mLs

17
Q

this can be a limiting factor if increased in diseased states?

A

diffusional distance

18
Q

in emphysema what is the limiting factor?

A

total surface area becomes decreased

19
Q

what is diffusing capacity?

A

ability of gas to diffuse from alveoli to blood

20
Q

what is important to note about diffusing capacity?

A

its the volume of gas that diffuses through the membrane each minute due to 1 mmHg pressure difference

21
Q

what is the pressure gradient for oxygen at rest? mean alveolar oxygen pressure? mean capillary oxygen pressure? this meant how much oxygen can diffuse into the blood?

A

11 mmHg

104 mmHg

93 mmHg

231 ml/min from pressure gradient (11 mmHg) x diffusing capacity (21 mL/min/mmHg)

22
Q

so during exercise, diffusing capacity for oxygen rises to 65 mL/min/mmHg which equates to 715 mL/min O2 delivered to blood during exercise, what is this increase due to?

A

opening of previously closed pulmonary capillaries to handle increased CO

better matching of ventilation to perfusion at all alveoli

note that CO2 diffusing capacity increases too