RESP

Question 1

key feature of klebsiella pneumonia and where is the CXR pathology

Answer 1

1) Red-currant jelly sputum

2) upper lobe cavitation

Question 2

differentiating factors for mycoplasma pneumonia(2)

Answer 2

1) haemolytic anaemia

2) Erythema multiforme

Question 3

which lung conditions do not cause clubbing(3)

Answer 3

1) Asthma
2) COPD
3) Pneumonia

Question 4

pyrazinamide side effects

Answer 4

1) arthralgia
2) rashes
3) Hyperuricaemia(gout)

Question 5

what is infliximab

Answer 5

TNF-alpha blocker- counteracts production of TNF -a in the synovium which leads to RA.

Question 6

Infliximab Contraindications

Answer 6

1) Congestive cardiac failure
2) Demyelinating diseases
3) hx of previous cancer
4) active infection

Question 7

endocrine side effect of long term steroid use

Answer 7

1) hyperglycaemia(hormones decrease the effectiveness of insulin in liver and make your liver dump more glucose into bloodstream)

Question 8

legionella pneumonia key features(4)

Answer 8

1) recent holiday
2) deranged LFTs
3) hyponatremia
4) lymphopenia

Question 9

demeclocycline(tetracycline with an interesting use)

Answer 9

1) used in SIADH, as it inhibits adh and causes nephrogenic diabetes insipidus. Used to treat SIADH which occurs in small cell cancer

Question 10

Examples of neuraminidase inhibitors

Answer 10

1) oseltamivir

2) Zanamivir

Question 11

symptoms of avian influenza(influenza A)

Answer 11

fever, dry cough, headache and diarrhoea.

Question 12

lupus pernio- what is it and which condition?

Answer 12

1) purple red blue lesion over fingers/nose/ears

2) Sarcoidosis

Question 13

drugs which can worsen psoriasis(red,flaky scaly)

Answer 13

1) beta-blockers

2) Lithium

Question 14

what is not a complication of pneumonia

Answer 14

Haemothorax

Question 15

treatment of acute pulmonary fibrosis

Answer 15

prednisolone- 0.5 mg /kg/day

Question 16

pseudomonas aeruginosa risk factors

Answer 16

1) Immunocompromised(HIV)

2) Moist surfaces( CVC), catheter

Question 17

allergic bronchopulmonary aspergillosis risk factors

Answer 17

1) CF

2) Asthma

Question 18

Histoplasmosis risk factors

Answer 18

1) bats
2) immunocompromised
3) young age

Question 19

Aspergilloma - who usually gets it

Answer 19

1) immunocompromised/ cavitating lung disease(emphysema/TB)

Question 20

Cryptococcal infection symptoms

Answer 20

1) confusion ataxia(meningoenchephalitis)

2) cough (pneumonia)

Question 21

Cryptococcal infection treatment regime

Answer 21

3 phases

1) Amphotericin B
2) fluctosine
3) fluconazole

Question 22

Squamous cell carcinoma neoplastic syndrome

Answer 22

• hypercalcaemia(PTH)

Question 23

Small cell carcinoma neoplastic

Answer 23

• ACTH- cushings

- Hyponatraemia- SIADH

Question 24

what is saccharopolyspora rectivirgula realated to

Answer 24

farmers lung(mouldy hay)

Question 25

aspergillusclavatus - relation to what job and condition

Answer 25

malt workers lung

Question 26

coal workers pneumoconiosis key features(2)

Answer 26

1) black sputum

2) numerous small pulmonary nodules on CXR

Question 27

pottery factor related to ?

Answer 27

silicosis

Question 28

pneumoconiosis(mining related) + R arthritis

Answer 28

caplan’s syndrome

Question 29

thermophilicactinomycetes - what EAA(extrinsic allergic alveolitis)

Answer 29

Mushroom workers lung

Question 30

what is not an extrinsic allergic alveolitis

Answer 30

asbestos exposure(lung fibrosis and chronic inflammation)