Reproductive System Flashcards

1
Q

What cells in the body can undergo meiosis? Somatic or germ cells?

A

Germ cells.

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2
Q

What is a germ cell?

A

Any biological cell that gives rise to the gametes of an organism that reproduces sexually.

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3
Q

Why are germ cells separated early from the rest of the cells during development?

A

So that they are not affected by signals to differentiate.

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4
Q

What does the epiblast give rise to during gastrulation?

A

The three germs layers; mesoderm, ectoderm and endoderm.

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5
Q

What is the difference between germ cells and germ layers?

A

Germ cells are the cells that give rise to gametes of a sexually reproducing organism. Germ layers are the three tissue layers formed during gastrulation.

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6
Q

Which germ layer gives rise to the gonads?

A

The intermediate mesoderm.

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7
Q

What tissues are derived from the intermediate mesoderm?

A

Tubule cells of the kidney and the urogenital system, including the gonads.

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8
Q

Are germ cells and gonads derived from the three germ layers?

A

No, the gonads are derived from the intermediate mesoderm, while the germ are separated from the three germ layers early on.

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9
Q

List the following structures in order of development: urogenital crest, kidneys and gonads, intermediate mesoderm.

A

Intermediate mesoderm, urogenital crest, kidneys and gonads.

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10
Q

Do the germ cells have intrinsic gender properties before entering the gonads?

A

No

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11
Q

What is the genital ridge a source of?

A

Male and female gonads

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12
Q

What chromosome in the SRY gene located on?

A

The Y sex chromosome

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13
Q

What sex chromosome combination is present in females?

A

XX

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14
Q

What sex chromosome combination is present in males?

A

XY

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15
Q

What does the Mullerian system drive?

A

Development of female characteristics, such as female anatomy and physiology and female behaviour.

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16
Q

What is anti-Mullarian hormone?

A

A hormone that causes female characteristics to retract in males.

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17
Q

What is the Wolffian system?

A

The male ductal system.

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18
Q

What is caused by switching on the SRY gene in the gonads?

A

Production of the anti-Mullarian hormone and the DHT to cause production of testosterone in the testis.

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19
Q

What is the meaning of “bipotential gonad”?

A

The gonads in the genital ridge have the potential to become male or female depending on the presence of the SRY gene.

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20
Q

What happens to the Mullarian ducts in a female?

A

The become the fallopian tubes, uterus and vagina.

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21
Q

What happens to the Wolffian ducts in the female?

A

They degenerate.

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22
Q

What happens to the Wollfian ducts in the male?

A

They develop into the vas deferens, prostate and the seminal vesicles.

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23
Q

What happens to the Mullarian ducts in the male system?

A

They degenerate due to AMH (anti-Mullarian hormone).

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24
Q

How do the male and female gonads differ in terms of structural organisation during development?

A

The male gonads are highly organised, while the gonads in females are not.

25
What does the genital tubercle become in males and in females?
Glans clitoris in the female and glans penis in the male.
26
What does the urethral fold become in the males and female?
Labia minora in the female and fold around the urethra in the male.
27
What does the labioscrotal swelling become in the male and in the female?
Labia majora in the female and scrotum in the male.
28
What structures outline the perineum (diamond shaped area between the thighs)?
Anterior: pubic symphysis. Posterior: coccyx Laterally: ischial tuberosities.
29
Why doesn't the ductus deferens lead sperm directly into the penis?
Because the testis developed in the abdomen before descending.
30
List the structures sperm passes following its production?
Seminiferous tubules, rete testis, efferent ducts, epididymis, ductus deferens
31
What is the function of the epididymus?
Sperm mature here (to become motile) and are stored here.
32
What is the optimal testis temperature?
34 degrees.
33
What is the function of the pampiniform plexus of testicular veins?
Temperature regulation
34
What is the function of the cremaster muscle?
Raises the testes for protection.
35
What is the function of the dartos muscle?
Temperature regulation.
36
What are three major cell types in the testis?
Germ cells, sertoulli cells and leydig cells.
37
What is semen?
Mix of seminal fluid and sperm.
38
What is the function of fluid secreted by the seminal vesicles?
Secrete sperm energy sources and prostaglandins to dilate the cervix.
39
What does the prostate gland secrete?
Citric acid (nourishment), seminal plasmin (antibiotic) and prostate-specific antigen (PSA) to liquify semen.
40
Why is PSA tested for to test for prostate cancer?
PSA should not be present in the blood, but if it is, the prostate structure is disrupted.
41
What is the function of the bulbourethral (Cowper's) glands?
Secrete viscous mucin to protect the urethra and act as lubricant during sex.
42
What is the function of the urethra?
Transport of semen outside.
43
What are the tree primary erectile tissue bodies in the penis?
Corpus cavernosum, corpus spongiosum and prepuce.
44
Where are the oocytes secreted from the fallopian tubes upon ovulation?
Peritoneal cavity then enter the fallopian tubes.
45
Which organ in females secretes oestrogen?
Ovaries.
46
What is the vulva?
Collective term for female external genitalia.
47
Where is the mons pubis located?
anterior to the pubic symphysis.
48
What is the vestibule in females?
Space for urethral opening and the vaginal orifice.
49
What is the fundus?
Body of the uterus.
50
What are the three layers of the uterus?
Perimetrium, myometrium, endometrium.
51
Which layer of the uterus is shed during menstruation?
The endometrium.
52
Which layer of the uterus is made of thick layers of smooth muscle?
Myometrium.
53
What is an XY female?
Someone who is chromosomally male but has external characteristics of a male due to problems with the SRY gene or hormones.
54
What is an XX male?
Chromosomally female with fragments of the Y chromosome.
55
If testosterone is produced by receptors for it are defective, will male or female genitalia develop?
Female.
56
What is Swyer syndrome?
XY chromosome (chromosomally male) with male phenotypes.
57
Is someone with Swyer syndrome able to undergo gestation?
Only with donor eggs and hormonal support.
58
Why do people with Swyer syndrome have their ovaries removed?
They are underdeveloped (streak ovaries) and increase the likelihood of cancer.
59
What is androgen insensitivity syndrome?
Normal testosterone with defective androgen receptors. XY with female genotype. Have internal testes that may be cancerous.