Reproduction Flashcards
how long does involution of the uterus take?
3-4 weeks
how long for placenta not to be passed to be classed as retained foetal membranes in cows?
> 24 hours
risk factors for metritis/ endometritis?
retained foetal membranes> abortion> dystocia> twins> milk fever> parturition induction
bacteria responsible for metritis/ endometritis
E.coli
Trueperella pyogenes
Dichelobacter nodosus
Fusobacterium necrophorum
purulent uterine discharge detectable in vagina up to 21 days post partum
metritis or endometritis?
metritis
purulent uterine discharge detectable in vagina > 21 days post partum
metritis or endometritis?
endometritis
which grade of metritis is this
enlarged uterus and uterine discharge but no pyrexia
grade 1
which grade of metritis is this
enlarged uterus, pyrexia >39.5 C, overt systemic illness of decreased milk yield, decreased appetite
called puerperal metritis
Grade 2
which grade of metritis is this
toxic metritis, signs of toxaemia, cold extremities and dullness
grade 3
accumulation of purulent discharge within uterus lumen
in the presence of a corpus luteum and closed cervix (on US)
cow not seen in heat
mixed infection
treated with PGF
pyometra
cow with nymphomania in anoestrus
on US cyst is: thin walled 2.5-2.7 mm fluid filled internal diameter >35mm for longer than 10 days cx
follicular ovarian cyst
when may a follicular ovarian cyst be in inactive?
if corpus luteum on other ovary present and <2cm
or
follicle has not been exposed to P4 from corpus luteum
how should you treat a follicular cyst if
<30 days in milk
> 30 days in milk
you’ve treated the cyst and the cow comes into heat. can the farmer AI her?
<30 days in milk: leave
> 30 days in milk: Burst with GnRH or progesterone in PRID
no. oocyte is old and infertile, wait till next oestrus
cow with nymphomania in anoestrus
on US cyst is: thick walled 5-6 mm fluid filled internal diameter 28-30mm for longer than 10 days cx fluid filled lacuna (in cl)
luteal cyst (lutenised follicular cyst)
what causes follicular cysts
any reason failure to ovulate
which uterine discharge score is this:
clear or translucent
0
which uterine discharge score is this:
flecks of white or off white pus
1
which uterine discharge score is this:
<50ml exudate containing <50% of white or off white material
2
which uterine discharge score is this:
> 50ml exudate containing purulent material, usually white or yellow but occasionally bloody
3
when does an FSH wave occur post partum, stimulating the first follicular wave?
2 weeks
successful ovulation of the first dominant follicle post partum depends on what factors?
size of dominant follicle
LH pulse frequency
IGF-I bioavailability
define abortion
any foetus dead or alive born 270 days or earlier after conception
primary or secondary agents cross fetomaternal barrier?
primary
primary or secondary agents cross pre damaged fetomaternal barrier?
secondary
Brucella abortus BVD Leptospirosis hardjo Neospora caninum BHV-1 Pararinfluenza 3 Bacillis licheniformis Fungi Campylobacterosis
Primary abortion agent, secondary abortion agent, non infectious cause of bovine abortion?
Primary abortion agents
which primary abortion agent is notifiable
brucella abortus
Salmonella
Listeria monocytogenes
Primary abortion agent, secondary abortion agent, non infectious cause of bovine abortion?
Secondary abortion agent
deficiencies in which nutrients can lead to abortion
Selenium
Vitamin A
Iodine
Non infectious causes of abortion?
Nutritional deficiencies Developmental abnormalities alfatoxin/ nitrate/nitrite toxins trauma hyperthermia twinning
Diagnosed by routine bulk milk tank sampling in dairy
dams blood and vaginal swab only if not milking
zoonotic
notifiable
brucellosis
Pregnant cow infected with BVD in days 0-95
sequalae?
abortion/ foetal reabsorption
non cytopathic form crosses feto-maternal barrier
Pregnant cow infected with BVD in days 95-120
sequalae?
Persistently infected calf born
non cytopathic form crosses feto-maternal barrier
would a PI calf born have positive or negative
antigens to BVD
antibodies to BVD
Clinical signs
any changes in clinical signs means what
positive antigens
negative antibodies
stunted and grows poorly
BVD virus inside a PI(non cytopathic form)> spontaneously converts to cytopathic form
» death of the PI from mucosal disease.
»>This usually happens age 6 months – 2 years.
Pregnant cow infected with BVD in days 120-285
sequalae?
seropositive foetus
congenital lesions
abortions due to placentitis
(non-cytopathic form crosses fetomaternal barrier)
sequalae if healthy cow infected with BVD non cytopathic form?
can cause diarrhoea, although it may be asymptomatic
abortions in pregnant cattle
sequalae if healthy (non PI) calf infected with non cytopathic BVD?
diarrhoea or may exacerbate other diseases (eg pneumonia)
Transmission route of BVD
nasal secretions, saliva or dung
How can a PI calf be a source of
a) horizontal transmission
b) vertical transmission
of BVD?
a) horizontal transmission= spread in nasal secretions, saliva and dung to other members of the herd
b) vertical transmission= pass to her own calf. her calf will be a PI.
can healthy cows become infected with cytopathic form BVD?
not commonly seen
how to diagnose BVD?
bulk milk test quarterly
- Bulk tank PCR detection limit one in 300
- 50% of herds seropositive to antigens probably
ear notch tissue test
check test: annual monitoring: 5 bloods per group to test antibodies
(seroconvert ie antigen> antibody over 3 weeks)
zoonotic
2 forms: hardjo - prajitno and hardjo-bovis
resides in kidneys and can be excreted for a long time
lower fertility, abortion, still birth, PI of repro tract, retained fetal membranes
dx by
bulk milk tank antibodies
serology by MAT (microscopic agglutination test)
identification of agent from aborted tissue, blood or urine by PCR
which bovine abortion agent is this?
Leptospirosis hardjo
Treatment for leptospirosis hardjo
dihydrostreptomycin
oxytetracycline
long course
early treatment reduces risk of latent carrier status