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Y4 Nephrology/Urology > Renal tumours > Flashcards

Renal tumours Flashcards

1
Q

What are the risk factors for renal cell carcinoma?

A

obesity
smoking
HTN
dialysis

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2
Q

What are the risk factors for transitional cell carcinoma?

A

smoking
aromatic amines
cyclophosphamide

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3
Q

what inheritable renal cell carcinoma is there?

A

VHL syndrome

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4
Q

what are the subtypes of renal cell carcinoma?

A

clear cell
papillary
chromophobe
collecting duct

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5
Q

what is the triad of renal cell carcinoma presentation?

A

haemtauria
loin mass
loin pain

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6
Q

what % of renal cell carcinoma is asymptomatic?

A

50%

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7
Q

what paraneoplastic features can occur with renal cell carcinoma?

A 
EPO - polycytheaemia 
PTHrP - hypercalcaemia 
renin - HTN 
ACTH - cushings
amyloidosis
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8
Q

what could be seen on CXR with renal cell carcinoma?

A

cannon ball mets

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9
Q

what staging is used for renal cell carcinoma?

A

Robsons staging

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10
Q

what is the management of renal cell carcinoma?

A

Radical nephrectomy
 Consider partial if small tumour or 1 kidney

Temsirolimus (mTOR inhibitor)
-for poor prognosis

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11
Q

where is the most common locatoin for transitional cell carcinoma?

A

bladder

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12
Q

what is the presentation of transitional cell carcinoma?

A

Painless haematuria
 Frequency, urgency, dysuria
 Urinary tract obstruction

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13
Q

what is the management of transitional cell carcinoma?

A

 Nephrouretectomy

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14
Q

what is another name of nephroblastoma?

A

Wilms tumour

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15
Q

what cells cause nephroblastoma?

A

Childhood tumour of primitive renal tubules and

mesenchymal cells

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16
Q

what is nephroblastoma associated with?

A

Chr 11 mutation

WAGR syndrome

17
Q

what does WAGR syndrome stand for?

A

wilms
aniridia
GU abnormalities
retardation

18
Q

state some benign neoplasms of the kidneys ?

A

cysts
renal paillary adenomas
oncocytoma
angiomyolipoma

19
Q

what condition is angiomyolipoma seen in?

A

tuberous sclerosis

20
Q

what neoplasm is associated with chronic infected staghorn calculi ?

A

SCC

Y4 Nephrology/Urology (17 decks)

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