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Y4 Nephrology/Urology > BPH > Flashcards

BPH Flashcards

1
Q

what cells are hyperplasic in BPH?

A

stromal

epithelial

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2
Q

What area is affected by BPH?

A

inner (transitional) layer

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3
Q

What molecule causes proliferation of stromal cells in the prostate?

A

DHT

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4
Q

what is DHT produced from?

A

produced from tetosterone in stromal cells by 5 alpha reductase enzyme

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5
Q

can a median sulcus be felt on DRE with BPH?

A

yes

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6
Q

what investigations should be done for BPH?

A 
U&Es, PSA
urinalysis 
TRUS and biopsy 
urodynamics
voiding diary
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7
Q

name a alpha blocker?

A

tamsulosin

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8
Q

name a 5alpha reductase inhibtor?

A

finasteride

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9
Q

what is a side effect of 5alpha reducatse inhibitors?

A

excreted in semen (use condoms)

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10
Q

what is a side effect of alpha blockers

A 
drowiness 
hypotension 
depression 
weight gain 
extra pyramidal signs
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11
Q

what is a complication of TURP?

A

impotence
retrograde ejaculation
uretheral stricture
incontinence

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Y4 Nephrology/Urology (17 decks)

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