renal tubular mechanisms Flashcards
absorption at proximal convoluted tubule
70% of K+, Na+, and H2O reabsorbed
100% glucose and amino acids
secretion at proximal convoluted tubule
100% PAH
majority of Na+ and H2O is reabsorbed in
proximal tubule
luminal membrane
brush border membrane
- increase surface area to expand reabsorption
is PAH completely secreted?
no, partially
descending limb of loop of henle reabsorbs
H2O
ascending limb of loop of Henle reabsorbs
Na+ and Cl-
NOT H2O
distal convoluted tubule reabsorbs
Na+ and Cl-
NOT H2O
aldosterone
steroid hormone
increases
- protein synthesis
- Na+/K+ pumps
- Na+ reabsorption
- K+ secretion
antidiuretic hormone (ADH)
increases H2O reabsorption
collecting duct
last place to change the composition of the filtrate
- fine tuning is performed by hormones
high ADH
reabsorb H2O
- concentrated urine
- low urine volume
low ADH
dont reabsorb H2O
dilute urine
large urine volume