renal concentration Flashcards

1
Q

importance of concentrating urine

A

concentrate urine to conserve water
can concentrate urine to the concentration of the interstitial fluid of the inner medulla

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2
Q

alcohol causes

A

decreased ADH release
increased urine
dehydration

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3
Q

ADH raises permeability to H2O by rising

A

cAMP and PKA
- fuse aquaporins to the luminal membrane

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4
Q

countercurrent multiplication

A

H2O reabsorbed from the descending limb of the loop of Henle
Na+, Cl-, but not reabsorbed from the ascending limb of the loop of Henle
can crease a 200 most concentration gradient
creates concentrated interstitial fluid of the inner medulla

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