important exam topics Flashcards

1
Q

renin activates

A

angiotensin I+II

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2
Q

renin causes

A

vasoconstriction

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3
Q

ACE

A

turns angiotensin I into angiotensin II

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4
Q

activation of vitamin D3 occurs in

A

proximal tubule cells

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5
Q

vitamin D3 is involved in

A

calcium regulation

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6
Q

erythropoietin stimulates production of

A

RBCs in the bone marrow

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7
Q

urea comes from

A

protein breakdown

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8
Q

uric acid comes from

A

ATP breakdown

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9
Q

creatinine comes from

A

muscle

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10
Q

increase in MAP causes

A

increased blood flow, GFR, and urine

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11
Q

increased GFR can also cause increased

A

Na+, Cl- filtration

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12
Q

macula densa cells detect

A

increased Na+, Cl- in filtration

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13
Q

macula dense cells constrict

A

afferent arterioles

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14
Q

contraction of afferent arteriole causes

A

decreased filtration

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15
Q

contraction of efferent arteriole causes

A

increased filtration

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16
Q

granular cells release

A

renin

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17
Q

macula dense cells are on

A

ascending limb of loop of Henle

18
Q

granular cells are on

A

afferent arteriole

19
Q

constriction of both afferent and efferent arterioles causes

A

decreased filtration

20
Q

constricted afferent arterioles inhibit

A

increased glomerular blood flow and capillary pressure

21
Q

sympathetic nervous system releases

A

NE, Ep

22
Q

release of NE, Ep act on

A

alpha 1 receptors

23
Q

release of NE, Ep causes

A

vasoconstriction of both afferent and efferent arterioles
- decreased renal blood flow

24
Q

increased GFR causes

A

increased urine

25
Q

inulin (GFR and filtration)

A

filtered
not reabsorbed
not secreted

26
Q

PAH (GFR and filtration)

A

filtered
not reabsorbed
completely secreted

27
Q

glucose (GFR and filtration)

A

filtered
completely reabsorbed
not secreted

28
Q

diabetes mellitus causes

A

glucose in urine
increased Urine volume

29
Q

0-GFR-RPF

A

scale of the amount of reabsorption/secretion
- RPF: complete secretion
- 0 : complete reabsorption

30
Q

proximal convoluted tubule reabsorbs

A

100% glucose + amino acids
70% K+, Na+, H2O

31
Q

proximal convoluted tubule secretes

A

100% PAH

32
Q

descending loop of henle reabsorbs

A

H2O

33
Q

ascending loop of Henle reabsorbs

A

Na+ and Cl-

34
Q

distal convoluted tubule reabsorbs

A

Na+ and Cl-

35
Q

aldosterone increases

A

protein synthesis
Na/K pumps
Na+ reabsorption
K+ secretion

36
Q

ADH increases

A

H2O reabsorption

37
Q

increase in renin causes an increase in

A

aldosterone, Na+ reabsorption, blood pressure, urine

38
Q

increase in ANP causes a decrease in

A

aldosterone, Na+ reabsorption, blood pressure, renin

39
Q

when the stretch receptor is stimulated what relaxes the voluntary sphincter

A

alpha-mn is inhibited

40
Q

when the stretch receptor is stimulated what causes the detrusser muscle to contact

A

parasympathetic NS

41
Q

ADH pathophysiology

A

increase in cAMP, PKA
bind aquaporins to luminal membrane
increase in H2O reabsorption