important exam topics Flashcards
renin activates
angiotensin I+II
renin causes
vasoconstriction
ACE
turns angiotensin I into angiotensin II
activation of vitamin D3 occurs in
proximal tubule cells
vitamin D3 is involved in
calcium regulation
erythropoietin stimulates production of
RBCs in the bone marrow
urea comes from
protein breakdown
uric acid comes from
ATP breakdown
creatinine comes from
muscle
increase in MAP causes
increased blood flow, GFR, and urine
increased GFR can also cause increased
Na+, Cl- filtration
macula densa cells detect
increased Na+, Cl- in filtration
macula dense cells constrict
afferent arterioles
contraction of afferent arteriole causes
decreased filtration
contraction of efferent arteriole causes
increased filtration
granular cells release
renin
macula dense cells are on
ascending limb of loop of Henle
granular cells are on
afferent arteriole
constriction of both afferent and efferent arterioles causes
decreased filtration
constricted afferent arterioles inhibit
increased glomerular blood flow and capillary pressure
sympathetic nervous system releases
NE, Ep
release of NE, Ep act on
alpha 1 receptors
release of NE, Ep causes
vasoconstriction of both afferent and efferent arterioles
- decreased renal blood flow
increased GFR causes
increased urine
inulin (GFR and filtration)
filtered
not reabsorbed
not secreted
PAH (GFR and filtration)
filtered
not reabsorbed
completely secreted
glucose (GFR and filtration)
filtered
completely reabsorbed
not secreted
diabetes mellitus causes
glucose in urine
increased Urine volume
0-GFR-RPF
scale of the amount of reabsorption/secretion
- RPF: complete secretion
- 0 : complete reabsorption
proximal convoluted tubule reabsorbs
100% glucose + amino acids
70% K+, Na+, H2O
proximal convoluted tubule secretes
100% PAH
descending loop of henle reabsorbs
H2O
ascending loop of Henle reabsorbs
Na+ and Cl-
distal convoluted tubule reabsorbs
Na+ and Cl-
aldosterone increases
protein synthesis
Na/K pumps
Na+ reabsorption
K+ secretion
ADH increases
H2O reabsorption
increase in renin causes an increase in
aldosterone, Na+ reabsorption, blood pressure, urine
increase in ANP causes a decrease in
aldosterone, Na+ reabsorption, blood pressure, renin
when the stretch receptor is stimulated what relaxes the voluntary sphincter
alpha-mn is inhibited
when the stretch receptor is stimulated what causes the detrusser muscle to contact
parasympathetic NS
ADH pathophysiology
increase in cAMP, PKA
bind aquaporins to luminal membrane
increase in H2O reabsorption