RENAL TUBULAR ACODOSIS

Question 1

renal tubular acidosis type II

Answer 1

• due to diminished capacity of the proximal tubule to reabsorb bicarbonate
• appearance of HBO3 in the urine
• low plasma HCO3 and acidic urine
• their is a significant amount of fixed acid lost in the urine
• FANCONI SYNDROME a defect in the proximal tubular transport process and carbonic anhydrase inhibitors

Question 2

renal tubular acidosis type I

Answer 2

• due to inability of the distal nephron to secrete and excrete fixed acid
• inability to form an acid urine
• urine pH > 5.5 - 6
• impairment transport of H+ and HCO3
• metabolic acidosis