afferent vs efferent arteriole Flashcards
kidney secretes
- renin in the circulation
- it its a circulating enzyme
- active form of vit D reabsorb calcium and phosphate in the gut 1, 25 dihydroxy
- erythropoietin
kidney secrets waste product
- urea
- creatinine
- less uric acid
nephron is located in
- cortex
loops of henle
- function is to create osmolar gradient
cortex
- proximal tubule - consume most ATP utilized by the kidney
- bowman’s capsule
- distal tubule- macula densa
- most metabolically active region
medulla
outer zone
inner zone
outer zone of the medulla
- collecting duct
- ADH
- reabsorption of water
inner zone of the medulla
- loop of henle
- MOST SUSCEPTIBLE TO ISCHEMIA
INCREASE BP
- kidney COSTRICTS to maintain renal blood flow
- at the afferent arterioles
DECREASE BP
- kidney DILATES to maintain blood flow
myogenic response to smooth muscle stretch
- greater constriction to main flow if changing in perfusion pressure
glomerular tubular feedback
- increase GFR deliver more NaCl to the distal tubule
- monitored by macula densa signal adenosine to control the resistance of the afferent arteriole (constriction) making GFR normal
macula densa regulates
- blood flow
- GFR
dilation of middle of renal series circuit
- lower over all resistance
- flow increases
- upstream pressure goes down
- downstream pressure goes up
constrict of middle renal series circuit
- flow decreases
- upstream pressure goes up
- downstream pressure goes down
afferent arterioles loses
- a lot pressure
- upstream
efferent arterioles loose
- 45 mm Hg
- increase resistance
- decrease flow to the capillaries
peritubular capillaries
- 7-8 mm Hg
- force promoting filtration
- low pressure reabsorbing capillaries
constrict efferent arteriole
- increase resistance
- increasing the flow
constrict efferent arteriole upstream
- increase pressure
- causing increase filtration
- increasing GFR
increase GFR
downstream
- increased fluid filtered per minute
- increased filtered greater amount of dissolved substance per minute to the proximal tubule
proximal tubule reabsorb
- of what have been filtered
consequence of too much increase GFR
- diuresis
constriction of afferent
- decrease glomerular capillary pressure
- decreasing GFR
- decrease fluid filtration
- decrease filtration of dissolved substances
- it reabsorb much greater on what is being filtered
- delivering less to the proximal tubule
conservation of water and electrolytes
- constrict afferent decreasing GFR
- less going to proximal tubule
