renal failure Flashcards

1
Q

ACUTE RENAL FAILURE
PRERENAL (GFR FAILURE)
REVERSIBLE

A
  • HYPOPERFUSION OF KIDNEY
  • structural lesions of renal vascular
  • generalized hypotension
  • drug effects on nephron perfusion
  • renal stenosis
  • DECREASE RENAL PERFUSION
  • hypovolemia
  • hemorrhage
  • diarrhea
  • vomiting
  • CHF
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2
Q

ACUTE RENAL FAILURE
INTRARENAL (GFR FAILURE)
REVERSIBLE

A
  • originate from DIRECT DAMAGE TO NEPHRON SYSTEM
  • either glomerulus or nephron
  • glomerulonephritis
  • interstitial nephritis
  • ischemia
  • rhabdomyolysis
  • sepsis
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3
Q

ACUTE RENAL FAILURE
POSTRENAL (GFR FAILURE)
REVERSIBLE

A
  • originate from URINARY TRACT OBSTRUCTION
  • kidney stone
  • prostate enlargement
  • spasm
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4
Q

PROBLEMS

A
  • INCREASE UREA
  • INCREASE CREATININE
  • HYPONATREMIA
  • excessive sweating HYPERNATREMIA
  • METABOLIC ACIDOSIS
  • RENIN ANGIOTENSIN ALDOSTERONE SYSTEM
  • CALCIUM ABSORPTION
  • ERYTHROPOIETIN ANEMIA
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5
Q
CHRONIC RENAL FAILURE
DIABETIC NEPHROPATHY (MCC)
A
  • IRREVERSIBLE LOSS OF NEPHRON
  • INCREASE glomerular capillary pressure
  • hyperfiltration
  • INCREASE work load
  • FIBROSIS
  • scarring, loss of additional nephrons
  • HALLMARK MICROALBUMINURIA
  • disease begins with INCREASE GFR above normal due to glomerular hypertension then DECREASE GFR
  • PROTEINURIA
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6
Q

most common cause of CHRONIC RENAL FAILURE

A
  • DIABETIC NEPHROPATHY (MCC)
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7
Q

second most common cause of CHRONIC RENAL FAILURE

A
  • HYPERTENSION
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